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SLC29A2 [plasma membrane]
Stable Identifier
R-HSA-54337
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
solute carrier family 29 (nucleoside transporters), member 2, Equilibrative nucleoside transporter 2, ENT2, Equilibrative nucleoside transporter 2 (Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter) (Equilibrative NBMPR-insensitive nucleoside transporter) (Nucleoside transporter, ei-type) (36 kDa nucleolar protein HNP36) (Hydrophobic nucleolar protein, 36 kDa) (Delayed-early response protein 12), Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, Equilibrative NBMPR-insensitive nucleoside transporter, Nucleoside transporter, ei-type, 36 kDa nucleolar protein HNP36, Hydrophobic nucleolar protein, 36 kDa, Delayed-early response protein 12
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Azathioprine ADME (Homo sapiens)
SLC29A1,2 transport 6MP from extracellular region to cytosol (Homo sapiens)
SLC29A1,2 [plasma membrane] (Homo sapiens)
SLC29A2 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)
SLC29A1-like proteins [plasma membrane] (Homo sapiens)
SLC29A2 [plasma membrane] (Homo sapiens)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
SLC29A2-like proteins [plasma membrane] (Homo sapiens)
SLC29A2 [plasma membrane] (Homo sapiens)
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)
SLC29A1-like proteins [plasma membrane] (Homo sapiens)
SLC29A2 [plasma membrane] (Homo sapiens)
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
SLC29A2-like proteins [plasma membrane] (Homo sapiens)
SLC29A2 [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
9478986
Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line
Crawford, CR
,
Belt, JA
,
Naeve, C
,
Patel, DH
J Biol Chem
1998
External Reference Information
External Reference
UniProt:Q14542 SLC29A2
Gene Names
SLC29A2, DER12, ENT2, HNP36
Chain
chain:1-456
Reference Genes
BioGPS Gene:3177 SLC29A2
COSMIC (genes):SLC29A2 SLC29A2
CTD Gene:3177 SLC29A2
dbSNP Gene:3177 SLC29A2
ENSEMBL:ENSG00000174669 SLC29A2
ENSEMBL_homo_sapiens_GENE:ENSG00000174669.12 SLC29A2
HGNC:11004 SLC29A2
KEGG Gene (Homo sapiens):3177 SLC29A2
Monarch:3177 SLC29A2
NCBI Gene:3177 SLC29A2
OMIM:602110 SLC29A2
UCSC:Q14542 SLC29A2
Reference Transcript
RefSeq:XM_017017637.1 SLC29A2
RefSeq:NM_001532.2 SLC29A2
RefSeq:NM_001300868.1 SLC29A2
RefSeq:XM_017017632.1 SLC29A2
RefSeq:NM_001300869.1 SLC29A2
Other Identifiers
11723794_a_at
11723795_a_at
11746651_a_at
1553540_PM_a_at
1553540_a_at
16740778
204717_PM_s_at
204717_s_at
3177
3378245
3378246
3378247
3378248
3378250
3378251
3378252
3378253
3378254
3378256
3378257
3378258
3378260
3378261
3378263
3378264
3378266
3378267
3378268
3378269
39661_s_at
7949619
A_23_P104705
A_23_P98294
GE81035
GO:0001504
GO:0003013
GO:0005215
GO:0005326
GO:0005337
GO:0005634
GO:0005730
GO:0005886
GO:0006836
GO:0006855
GO:0015205
GO:0015207
GO:0015208
GO:0015210
GO:0015211
GO:0015212
GO:0015213
GO:0015851
GO:0015853
GO:0015854
GO:0015858
GO:0015860
GO:0015861
GO:0015862
GO:0016020
GO:0016323
GO:0016324
GO:0032238
GO:0035340
GO:0035344
GO:0035364
GO:0043226
GO:0055085
GO:0072531
GO:0150104
GO:1901642
GO:1903716
GO:1903791
GO:1904823
HMNXSV003027076
HMNXSV003037005
Hs2.32951.1.S1_3p_s_at
ILMN_1730809
PH_hs_0002772
TC11001966.hg
X86681_at
g2811136_3p_a_at
Participates
as a member of
SLC29A1,2 [plasma membrane] (Homo sapiens)
SLC29A2-like proteins [plasma membrane] (Homo sapiens)
as a candidate of
SLC29A1-like proteins [plasma membrane] (Homo sapiens)
Inferred To
Homologues of SLC29A2 [plasma membrane]
(Dictyostelium discoideum)
ent-6 [plasma membrane]
(Caenorhabditis elegans)
Ent1 [plasma membrane]
(Drosophila melanogaster)
SLC29A2 [plasma membrane]
(Bos taurus)
SLC29A2 [plasma membrane]
(Canis familiaris)
SLC29A2 [plasma membrane]
(Dictyostelium discoideum)
SLC29A2 [plasma membrane]
(Plasmodium falciparum)
SLC29A2 [plasma membrane]
(Sus scrofa)
Slc29a2 [plasma membrane]
(Mus musculus)
Slc29a2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001287797.1
,
XP_016873126.1
,
NP_001287798.1
,
XP_016873121.1
,
NP_001523.2
Guide to Pharmacology - Targets
1118
OpenTargets
ENSG00000174669
HPA
ENSG00000174669-SLC29A2
GeneCards
Q14542
Ensembl
ENST00000544554
,
ENSP00000444870
,
ENST00000546034
,
ENSP00000311250
,
ENST00000619145
,
ENSP00000440329
,
ENST00000357440
,
ENSP00000439456
,
ENSP00000442116
,
ENST00000541567
,
ENSG00000174669
,
ENSP00000481944
,
ENSP00000350024
,
ENST00000540386
,
ENST00000311161
PRO
Q14542
Pharos - Targets
Q14542
HMDB Protein
HMDBP03195
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