Peptide transfer from P-site to A-site (peptide bond formation)

Stable Identifier
R-HSA-5389857
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Peptide transfer from P-site to A-site (peptide bond formation)
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As inferred from bovine homologs, the ribosome catalyzes formation of a peptide bond between the aminoacyl group of the aminoacyl-tRNA at the A-site and the peptidyl-tRNA at the P-site. The result is a polypeptide, longer by one amino acid, attached to the tRNA at the A-site by an ester bond. A deacylated tRNA remains at the P-site. 55S ribosomes associate with the inner mitochondrial membrane and the translation products are cotranslationally inserted into the inner membrane.
Participants
Input
Output
Participates
as an event of
Inferred From
Peptide transfer from P-site to A-site (peptide bond formation) (Bos taurus)
Authored
May, B  (2014-04-26)
Reviewed
Chrzanowska-Lightowlers, ZM  (2014-08-29)
Spremulli, LL  (2014-09-20)
Created
May, B  (2014-04-30)
Cite Us!