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MRPL45 [mitochondrial inner membrane]
Stable Identifier
R-HSA-5368224
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
39S ribosomal protein L45, mitochondrial, RM45_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Mitochondrial translation (Homo sapiens)
Mitochondrial translation elongation (Homo sapiens)
55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
Peptide transfer from P-site to A-site (peptide bond formation) (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation initiation (Homo sapiens)
39S subunit binds 28S subunit:mRNA:fMet-tRNA (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation termination (Homo sapiens)
55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
Hydrolysis of GTP and dissociation of 28S and 39S subunits (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
MRRF binds 55S ribosome:mRNA:tRNA (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL45 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BRJ2 MRPL45
Gene Names
MRPL45
Chain
transit peptide:1-, chain:-306
Reference Genes
ENSEMBL:ENSG00000277936 MRPL45
ENSEMBL_homo_sapiens_GENE:ENSG00000277936.4 MRPL45
HGNC:16651 MRPL45
OMIM:611850 MRPL45
UCSC:Q9BRJ2 MRPL45
Other Identifiers
11718285_s_at
11757365_s_at
11758795_at
16833605
224479_PM_s_at
224479_s_at
3719703
3719706
3719707
3719708
3719709
3719710
3719712
3719713
3719714
3719715
3760808
3760811
3760812
3760813
3760816
45578_s_at
65527_at
8006762
84311
A_23_P113623
A_32_P9575
GE83390
GO:0003723
GO:0005515
GO:0005739
GO:0005743
GO:0005762
GO:0005840
GO:0032543
GO:0043226
GO:0140053
GO:1990904
HMNXSV003054544
HMNXSV003055881
ILMN_1748650
ILMN_1808301
PH_hs_0001703
TC17000459.hg
g13623270_3p_s_at
Participates
as a component of
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
Inferred To
mrpl-45 [mitochondrial inner membrane]
(Caenorhabditis elegans)
Mrpl45 [mitochondrial inner membrane]
(Mus musculus)
Mrpl45 [mitochondrial inner membrane]
(Rattus norvegicus)
mRpL45 [mitochondrial inner membrane]
(Drosophila melanogaster)
mrpl45 [mitochondrial inner membrane]
(Danio rerio)
MRPL45 [mitochondrial inner membrane]
(Bos taurus)
MRPL45 [mitochondrial inner membrane]
(Canis familiaris)
MRPL45 [mitochondrial inner membrane]
(Gallus gallus)
MRPL45 [mitochondrial inner membrane]
(Sus scrofa)
Cross References
OpenTargets
ENSG00000278845
GeneCards
Q9BRJ2
Ensembl
ENSG00000277936
,
ENST00000621878
,
ENSP00000483030
PRO
Q9BRJ2
Pharos - Targets
Q9BRJ2
PDB
7L08
,
6ZSB
,
7OIE
,
7L20
,
7QI5
,
6VMI
,
7OIC
,
7O9K
,
7PO4
,
6ZSE
,
3J9M
,
7OF2
,
7A5H
,
8PK0
,
7A5G
,
6ZSC
,
6NU2
,
7OF0
,
5OOM
,
7QH6
,
7OI9
,
3J7Y
,
7ODR
,
7OF4
,
7A5J
,
7OI7
,
6ZS9
,
8OIR
,
6ZM6
,
6ZM5
,
6VLZ
,
7OIA
,
7OF7
,
6I9R
,
7QI4
,
6ZSA
,
7O9M
,
7OID
,
7QI6
,
7OF3
,
7A5I
,
6NU3
,
7OI6
,
7OG4
,
6ZSD
,
7A5F
,
5OOL
,
8ANY
,
7ODS
,
7QH7
,
7OF5
,
7A5K
,
7OI8
,
7PD3
,
6ZSG
,
8QSJ
,
7OIB
,
8OIT
,
7ODT
,
7OF6
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6NZI2 PTRF
2
PTRF [nucleoplasm]
(R-HSA-74981)
CAVIN1 [plasma membrane]
(R-HSA-9714278)
0.556
3
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