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DT:HBEGF:CD9 is transported from clathrin-coated vesicle to endosome
Stable Identifier
R-HSA-5336413
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Corynephage beta
Compartment
clathrin-coated endocytic vesicle membrane
,
endocytic vesicle membrane
ReviewStatus
5/5
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Uptake and actions of bacterial toxins (Homo sapiens)
Uptake and function of diphtheria toxin (Homo sapiens)
DT:HBEGF:CD9 is transported from clathrin-coated vesicle to endosome (Homo sapiens)
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The target cell clathrin-coated vesicle containing diphtheria toxin (DT A:B) in a complex with target cell proteins HBEGF and CD9 is transformed into an endocytic vesicle (Murphy 2011).
Literature References
PubMed ID
Title
Journal
Year
22069710
Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process
Murphy, JR
Toxins (Basel)
2011
Participants
Input
DT:HBEGF:CD9 [clathrin-coated endocytic vesicle membrane]
(Homo sapiens)
Output
DT:HBEGF:CD9 [endocytic vesicle membrane]
(Homo sapiens)
Participates
as an event of
Uptake and function of diphtheria toxin (Homo sapiens)
Disease
Name
Identifier
Synonyms
diphtheria
DOID:11405
corynebacterium infection
Authored
D'Eustachio, P (2014-03-05)
Reviewed
Liu, S (2014-11-19)
Created
D'Eustachio, P (2014-03-03)
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