Reactome | COX7A1 [mitochondrial inner membrane]

COX7A1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5336152

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Cytochrome c oxidase subunit 7A1, mitochondrial, CX7A1_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Metabolic Genes (Homo sapiens)
        
        Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1 [mitochondrial inner membrane] (Homo sapiens)
        
        Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P24310 COX7A1

Gene Names

COX7A1, COX7AH

Chain

transit peptide:1-21, chain:22-79

Reference Genes

BioGPS Gene:1346 COX7A1

COSMIC (genes):COX7A1 COX7A1

CTD Gene:1346 COX7A1

dbSNP Gene:1346 COX7A1

ENSEMBL:ENSG00000161281 COX7A1

HGNC:2287 COX7A1

KEGG:hsa:1346 COX7A1

Monarch:1346 COX7A1

NCBI Gene:1346 COX7A1

OMIM:123995 COX7A1

UCSC:P24310 COX7A1

Reference Transcript

RefSeq:NM_001864.3 COX7A1

Other Identifiers

11717430_s_at

1346

16871622

204570_PM_at

204570_at

3860295

3860297

3860298

3860299

3860300

3860301

3860302

3860303

3860304

39031_at

8036284

A_23_P67661

GE54301

GE85169

GO:0002082

GO:0003824

GO:0004129

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005746

GO:0005751

GO:0006091

GO:0006119

GO:0006123

GO:0007005

GO:0016020

GO:0016491

GO:0043226

GO:0055085

GO:0065003

GO:0097250

GO:0098803

GO:1902600

HMNXSV003008322

ILMN_1662419

M83186_at

PH_hs_0019743

TC19001463.hg

g4502986_3p_at

Participates

as an output of

COX7A1 gene expression is stimulated by EBF2 (Homo sapiens)

as a member of

COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)

Inferred To

cox7a2 [mitochondrial inner membrane] (Xenopus tropicalis)

cox7a2a [mitochondrial inner membrane] (Danio rerio)

cox7a1 [mitochondrial inner membrane] (Danio rerio)

COX7AL [mitochondrial inner membrane] (Drosophila melanogaster)

COX7A1 [mitochondrial inner membrane] (Bos taurus)

COX7A1 [mitochondrial inner membrane] (Canis familiaris)

COX7A1 [mitochondrial inner membrane] (Sus scrofa)

COX7A2 [mitochondrial inner membrane] (Gallus gallus)

Homologues of COX7A1 [mitochondrial inner membrane] (Danio rerio)

Homologues of COX7A1 [mitochondrial inner membrane] (Drosophila melanogaster)

COX7A [mitochondrial inner membrane] (Drosophila melanogaster)

Cox7a1 [mitochondrial inner membrane] (Mus musculus)

COX7AL2 [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000292907, ENSP00000292907

OpenTargets

ENSG00000161281

HPA

ENSG00000161281-COX7A1

PRO

P24310

Pharos - Targets

P24310

HMDB Protein

HMDBP02366

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:P28331-2 NDUFS1			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:O75190-2 DNAJB6			0.556	3

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