Reactome | MPI [cytosol]

MPI [cytosol]

Stable Identifier

R-HSA-532511

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

MPI, Mannose-6-phosphate isomerase, MPI_HUMAN

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Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Synthesis of GDP-mannose (Homo sapiens)
        
        MPI isomerises Fru6P to Man6P (Homo sapiens)
        
        MPI [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P34949 MPI

Gene Names

MPI, PMI1

Chain

initiator methionine:, chain:2-423

Reference Genes

BioGPS Gene:4351 MPI

COSMIC (genes):MPI MPI

CTD Gene:4351 MPI

dbSNP Gene:4351 MPI

ENSEMBL:ENSG00000178802 MPI

ENSEMBL_homo_sapiens_GENE:ENSG00000178802.18 MPI

HGNC:7216 MPI

KEGG Gene (Homo sapiens):4351 MPI

Monarch:4351 MPI

NCBI Gene:4351 MPI

OMIM:154550 MPI

UCSC:P34949 MPI

Reference Transcript

Other Identifiers

11744376_a_at

11759552_at

16803103

202472_PM_at

202472_at

3601956

3601959

3601960

3601963

3601964

3601965

3601969

3601971

3601973

3601974

3601975

3601977

3601979

3601981

3601983

3601985

36673_at

4351

57208_at

7984922

A_14_P123672

A_14_P134474

A_23_P60579

GE60007

GE861479

GO:0003824

GO:0004476

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005829

GO:0005975

GO:0008270

GO:0009298

GO:0016853

GO:0043226

GO:0046872

GO:0055086

GO:0061611

GO:0070062

GO:1901135

HMNXSV003030431

HMNXSV003040041

ILMN_1761262

PH_hs_0004363

TC15000687.hg

X76057_at

g4505234_3p_at

g4505234_3p_x_at

p5666

Other forms of this molecule

MPI A38Gfs*26 [cytosol]

MPI M138T [cytosol]

MPI S102L [cytosol]

MPI R295H [cytosol]

MPI R219Q [cytosol]

Inferred To

MPI [cytosol] (Bos taurus)

MPI [cytosol] (Caenorhabditis elegans)

MPI [cytosol] (Canis familiaris)

MPI [cytosol] (Danio rerio)

MPI [cytosol] (Dictyostelium discoideum)

MPI [cytosol] (Drosophila melanogaster)

MPI [cytosol] (Gallus gallus)

MPI [cytosol] (Mus musculus)

MPI [cytosol] (Plasmodium falciparum)

MPI [cytosol] (Rattus norvegicus)

MPI [cytosol] (Saccharomyces cerevisiae)

MPI [cytosol] (Schizosaccharomyces pombe)

MPI [cytosol] (Sus scrofa)

MPI [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001276086.1, NP_002426.1, NP_001276085.1

OpenTargets

ENSG00000178802

ZINC - Substances

MPI_HUMAN

ZINC target

P34949

PRO

P34949

IntEnz

5.3.1.8

GeneCards

P34949

HPA

ENSG00000178802-MPI

Ensembl

ENST00000323744, ENST00000352410, ENSP00000318318, ENSP00000318192, ENSG00000178802

Pharos - Targets

P34949

ZINC - Predictions - Purchasable

MPI_HUMAN

Orphanet

16459

HMDB Protein

HMDBP00797

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