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HDAC6:VCP:protein aggregates
Stable Identifier
R-HSA-5324663
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to heat stress (Homo sapiens)
HSF1 activation (Homo sapiens)
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Homo sapiens)
HDAC6:VCP:protein aggregates [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
17785525
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
Genes Dev.
2007
Participants
components
HDAC6 [cytosol] (Homo sapiens)
Ub-protein aggregates [cytosol]
VCP [cytosol] (Homo sapiens)
Participant Of
output
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates
Inferred To
HDAC6:VCP:protein aggregates [cytosol] (Bos taurus)
HDAC6:VCP:protein aggregates [cytosol] (Canis familiaris)
HDAC6:VCP:protein aggregates [cytosol] (Danio rerio)
HDAC6:VCP:protein aggregates [cytosol] (Rattus norvegicus)
HDAC6:VCP:protein aggregates [cytosol] (Saccharomyces cerevisiae)
HDAC6:VCP:protein aggregates [cytosol] (Xenopus tropicalis)
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