defective AXIN1 gene [nucleoplasm]

Stable Identifier
R-HSA-5251553
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SNU-475 exon 1 and 2 deletion
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
10700176 AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

Miwa, N, Tokino, T, Furukawa, Y, Fujita, M, Daigo, Y, Nishiwaki, T, Nakamura, Y, Kato, T, Satoh, S, Kawasoe, T, Yamaoka, Y, Murata, M, Sasaki, Y, Ishiguro, H, Shimano, T, Imaoka, S

Nat. Genet. 2000
External Reference Information
External Reference
ENSEMBL:ENSG00000103126 AXIN1
Gene Names
AXIN1, AXIN
Participates
as an input of
Other forms of this molecule
AXIN1 gene [nucleoplasm]
Modified Residues
Name
Deletion of residues 364543 to 402673
Disease
Name Identifier Synonyms
hepatocellular carcinoma DOID:684 adult Hepatoma, adult primary Liver carcinoma, Liver carcinoma, Hepatocellular carcinoma (morphologic abnormality), primary carcinoma of liver (disorder), hepatoma, Hepatoma, adult primary hepatocellular carcinoma, primary carcinoma of the liver cells, Hepatocellular carcinoma (clinical), Liver carcinoma, HCC, carcinoma of liver, specified as primary
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
COSMIC
Cite Us!