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botE:SV2:GT1b [synaptic vesicle membrane]
Stable Identifier
R-HSA-5244509
Type
Complex
Species
Homo sapiens
Related Species
Clostridium botulinum
Compartment
synaptic vesicle membrane
Synonyms
BoNT/E:SV2:GT1b
GO Cellular Component
host cell synaptic vesicle membrane
(0098585)
Locations in the PathwayBrowser
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Neurotoxicity of clostridium toxins (Homo sapiens)
Toxicity of botulinum toxin type E (botE) (Homo sapiens)
botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
botE:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botE:SV2:GT1b [synaptic vesicle membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
2116911
Botulinum neurotoxin type E fragmented with endoproteinase Lys-C reveals the site trypsin nicks and homology with tetanus neurotoxin
Giménez, JA
,
DasGupta, BR
Biochimie
1990
Participants
components
BoNT/E HC:LC dimer [synaptic vesicle membrane]
(Clostridium botulinum)
GT1b [synaptic vesicle membrane]
SV2A,B [synaptic vesicle membrane]
(Homo sapiens)
Participates
as an output of
botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
as an input of
botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)
Disease
Name
Identifier
Synonyms
botulism
DOID:11976
Botulism (disorder), Intoxication with Clostridium botulinum toxin, Botulism, Infection due to clostridium botulinum, Botulism, Foodborne botulism, botulism, Botulism, Botulism, Botulism, Food poisoning due to Clostridium botulinum, Botulism poisoning
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