WDR5 binds Me2sR3-replicative histone H3

Stable Identifier
R-HSA-5225602
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Symmetric dimethylation of histone H3 arginine-3 (H3R2) enhances binding of WDR5, a component of the coactivator complexes MLL, SET1A, SET1B, NLS1 and ATAC (Migliori et al. 2012).

Literature References
PubMed ID Title Journal Year
22231400 Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance

Migliori, V, Müller, J, Phalke, S, Low, D, Bezzi, M, Mok, WC, Sahu, SK, Gunaratne, J, Capasso, P, Bassi, C, Cecatiello, V, De Marco, A, Blackstock, W, Kuznetsov, V, Amati, B, Mapelli, M, Guccione, E

Nat. Struct. Mol. Biol. 2012
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