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SV2B [plasma membrane]
Stable Identifier
R-HSA-5216103
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Synaptic vesicle glycoprotein 2B, SV2B_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Neurotoxicity of clostridium toxins (Homo sapiens)
Toxicity of botulinum toxin type A (botA) (Homo sapiens)
botA HC:LC binds SV2A, B, or C and GT1b on the target cell surface (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botA HC:LC dimer:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botA:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botA HC:LC dimer:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
Toxicity of botulinum toxin type D (botD) (Homo sapiens)
botD HC:LC binds SV2A or B or C and GD2 on the target cell surface (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botD:SV2:GD2 [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botD:SV2:GD2 internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botD:SV2:GD2 [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
Toxicity of botulinum toxin type E (botE) (Homo sapiens)
botE HC:LC binds SV2A or B and GT1b on the target cell surface (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botE:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botE:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
Toxicity of botulinum toxin type F (botF) (Homo sapiens)
botF HC:LC binds SV2A or B or C and GT1b on the target cell surface (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botF:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
botF:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botF:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2B [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7L1I2 SV2B
Gene Names
SV2B, KIAA0735
Chain
chain:1-683
Reference Genes
BioGPS Gene:9899 SV2B
COSMIC (genes):SV2B SV2B
CTD Gene:9899 SV2B
dbSNP Gene:9899 SV2B
ENSEMBL:ENSG00000185518 SV2B
ENSEMBL_homo_sapiens_GENE:ENSG00000185518.12 SV2B
HGNC:16874 SV2B
KEGG Gene (Homo sapiens):9899 SV2B
Monarch:9899 SV2B
NCBI Gene:9899 SV2B
OMIM:185861 SV2B
UCSC:Q7L1I2 SV2B
Reference Transcript
RefSeq:NM_001323039.2 SV2B
RefSeq:NM_001323031.2 SV2B
RefSeq:NM_014848.6 SV2B
RefSeq:NM_001323040.2 SV2B
RefSeq:NM_001323032.2 SV2B
RefSeq:XM_005254998.3 SV2B
RefSeq:NM_001323037.2 SV2B
RefSeq:XM_017022761.1 SV2B
RefSeq:XM_017022762.1 SV2B
RefSeq:NM_001323038.2 SV2B
RefSeq:NM_001167580.2 SV2B
Other Identifiers
11743495_s_at
11746334_a_at
16805124
205551_PM_at
205551_at
232426_PM_at
232426_at
244717_PM_x_at
244717_x_at
32614_at
3608639
3608643
3608655
3608656
3608657
3608662
3608664
3608665
3608666
3608667
3608668
3608669
3608674
3608675
3608677
3608678
3608679
3608680
3608681
3608682
3608690
3608691
3608692
3608694
43866_at
44874_at
7986195
86233_at
9899
A_14_P129913
A_23_P100022
A_33_P3337617
GE53448
GE56405
GO:0001669
GO:0005215
GO:0005515
GO:0005886
GO:0006836
GO:0007268
GO:0008021
GO:0016020
GO:0016192
GO:0022857
GO:0023052
GO:0030672
GO:0031410
GO:0043226
GO:0045202
GO:0055065
GO:0055085
GO:0099509
GO:2000300
HMNXSV003015589
HMNXSV003027358
Hs.181612.0.A1_3p_at
Hs.181612.0.A1_3p_x_at
Hs.21754.0.S1_3p_at
ILMN_1806306
PH_hs_0000862
PH_hs_0001889
TC15000877.hg
TC15002370.hg
g7662269_3p_at
Participates
as a member of
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
Other forms of this molecule
SV2B [synaptic vesicle membrane]
Cross References
RefSeq
XP_016878250.1
,
NP_055663.1
,
NP_001309966.1
,
NP_001309961.1
,
NP_001309967.1
,
NP_001309968.1
,
NP_001161052.1
,
NP_001309960.1
,
XP_005255055.1
,
NP_001309969.1
,
XP_016878251.1
OpenTargets
ENSG00000185518
GeneCards
Q7L1I2
HPA
ENSG00000185518-SV2B
Ensembl
ENSP00000443243
,
ENSP00000377779
,
ENST00000545111
,
ENST00000557410
,
ENSP00000450992
,
ENST00000330276
,
ENSG00000185518
,
ENST00000394232
,
ENSP00000332818
PRO
Q7L1I2
Pharos - Targets
Q7L1I2
HMDB Protein
HMDBP08021
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