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glc-fuc-ADAMTS2 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-5173206
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
O-fuc-ADAMTS2, ADAMTS2, A disintegrin and metalloproteinase with thrombospondin motifs 2, ATS2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-glycosylation of TSR domain-containing proteins (Homo sapiens)
B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)
glc-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
glc-fuc-ADAMTS2 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95450 ADAMTS2
Gene Names
ADAMTS2, PCINP, PCPNI
Chain
signal peptide:1-29, propeptide:30-253, chain:254-1211
Reference Genes
BioGPS Gene:9509 ADAMTS2
COSMIC (genes):ADAMTS2 ADAMTS2
CTD Gene:9509 ADAMTS2
dbSNP Gene:9509 ADAMTS2
ENSEMBL:ENSG00000087116 ADAMTS2
ENSEMBL_homo_sapiens_GENE:ENSG00000087116.17 ADAMTS2
HGNC:218 ADAMTS2
KEGG Gene (Homo sapiens):9509 ADAMTS2
Monarch:9509 ADAMTS2
NCBI Gene:9509 ADAMTS2
OMIM:604539 ADAMTS2
UCSC:O95450 ADAMTS2
Reference Transcript
RefSeq:NM_021599.3 ADAMTS2
RefSeq:NM_014244.4 ADAMTS2
Other Identifiers
11730504_at
11743205_x_at
17003640
214454_PM_at
214454_at
214535_PM_s_at
214535_s_at
226311_PM_at
226311_at
2889914
2889915
2889917
2889925
2889928
2889932
2889934
2889935
2889936
2889939
2889941
2889942
2889943
2889946
2889950
2889951
2889952
2889953
2889955
2889956
2889957
2889967
2889980
2890000
2890009
2890012
2890013
34494_at
49102_at
8116272
9509
A_23_P321307
A_24_P251866
A_33_P3409649
GE55156
GE846810
GO:0003824
GO:0004222
GO:0005576
GO:0006508
GO:0007283
GO:0008233
GO:0008237
GO:0008270
GO:0016485
GO:0016787
GO:0022414
GO:0030198
GO:0030199
GO:0030312
GO:0030324
GO:0030574
GO:0031012
GO:0043588
GO:0046872
GO:0048856
GO:0051604
GO:0062023
GO:0140096
HMNXSV003007689
HMNXSV003024733
Hs.120330.0.S1_3p_at
Hs.120330.1.S1_3p_a_at
Hs.120330.1.S1_3p_x_at
Hs.8687.0.A1_3p_at
ILMN_1796628
ILMN_1811765
PH_hs_0002101
PH_hs_0006647
TC05002130.hg
TC05003380.hg
Participates
as a candidate of
glc-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
ADAMTS2 [extracellular region]
ADAMTS2 [endoplasmic reticulum lumen]
O-fuc-ADAMTS2 [endoplasmic reticulum lumen]
Inferred To
rsc22 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
glc-fuc-ADAMTS2 [endoplasmic reticulum lumen]
(Bos taurus)
glc-fuc-ADAMTS2 [endoplasmic reticulum lumen]
(Canis familiaris)
glc-fuc-ADAMTS2 [endoplasmic reticulum lumen]
(Gallus gallus)
glc-fuc-ADAMTS2 [endoplasmic reticulum lumen]
(Mus musculus)
glc-fuc-ADAMTS2 [endoplasmic reticulum lumen]
(Rattus norvegicus)
glc-fuc-ADAMTS2 [endoplasmic reticulum lumen]
(Sus scrofa)
Modified Residues
Name
O-fucosyl-L-serine (ChEBI:76521) at unknown position
Modification
beta-D-glucosyl-(1->3)-alpha-L-fucosyl group
PsiMod Name
O-fucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to an O-fucosylserine.
Cross References
RefSeq
NP_067610.1
,
NP_055059.2
Guide to Pharmacology - Targets
1675
OpenTargets
ENSG00000087116
HPA
ENSG00000087116-ADAMTS2
GeneCards
O95450
Ensembl
ENSP00000274609
,
ENSP00000251582
,
ENST00000274609
,
ENST00000251582
,
ENSG00000087116
PRO
O95450
Pharos - Targets
O95450
Orphanet
15083
HMDB Protein
HMDBP10018
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