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O-fuc-SPON2 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-5173038
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
SPON2, Spondin-2, SPON2_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with O-glycosylation of proteins (Homo sapiens)
Defective B3GALTL causes PpS (Homo sapiens)
Defective B3GALTL does not transfer glucose to O-fucosyl-proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SPON2 [endoplasmic reticulum lumen] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-glycosylation of TSR domain-containing proteins (Homo sapiens)
B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SPON2 [endoplasmic reticulum lumen] (Homo sapiens)
POFUT2 transfers fucose to TSR domain-containing proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SPON2 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BUD6 SPON2
Gene Names
SPON2, DIL1, UNQ435/PRO866
Chain
signal peptide:1-26, chain:27-331
Reference Genes
BioGPS Gene:10417 SPON2
COSMIC (genes):SPON2 SPON2
CTD Gene:10417 SPON2
dbSNP Gene:10417 SPON2
ENSEMBL:ENSG00000159674 SPON2
ENSEMBL_homo_sapiens_GENE:ENSG00000159674.12 SPON2
HGNC:11253 SPON2
KEGG Gene (Homo sapiens):10417 SPON2
Monarch:10417 SPON2
NCBI Gene:10417 SPON2
OMIM:605918 SPON2
UCSC:Q9BUD6 SPON2
Reference Transcript
RefSeq:NM_001128325.2 SPON2
RefSeq:NM_012445.3 SPON2
RefSeq:NM_001199021.1 SPON2
Other Identifiers
10417
11716525_a_at
11716526_x_at
11754601_s_at
218638_PM_s_at
218638_s_at
2756967
2756968
2756969
2756970
2756981
2756983
2756985
2756987
2756988
2757032
2757033
52576_s_at
63361_at
8098870
A_23_P121533
GE58498
GO:0001530
GO:0002376
GO:0002448
GO:0003823
GO:0005515
GO:0005576
GO:0005615
GO:0007155
GO:0008228
GO:0008289
GO:0016192
GO:0030312
GO:0031012
GO:0032496
GO:0032755
GO:0032760
GO:0042742
GO:0043152
GO:0043226
GO:0045087
GO:0046872
GO:0050832
GO:0051607
GO:0060907
GO:0070062
GO:0071222
GO:0098542
HMNXSV003034003
ILMN_1676099
g6912681_3p_s_at
Participates
as a candidate of
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
SPON2 [endoplasmic reticulum lumen]
glc-fuc-SPON2 [endoplasmic reticulum lumen]
Inferred To
O-fuc-SPON2 [endoplasmic reticulum lumen]
(Bos taurus)
O-fuc-SPON2 [endoplasmic reticulum lumen]
(Gallus gallus)
O-fuc-SPON2 [endoplasmic reticulum lumen]
(Mus musculus)
O-fuc-SPON2 [endoplasmic reticulum lumen]
(Plasmodium falciparum)
O-fuc-SPON2 [endoplasmic reticulum lumen]
(Rattus norvegicus)
SPON2 [endoplasmic reticulum lumen]
(Canis familiaris)
SPON2 [endoplasmic reticulum lumen]
(Sus scrofa)
spon2 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
spon2b [endoplasmic reticulum lumen]
(Danio rerio)
mspo [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Modified Residues
Name
O-fucosyl-L-serine at unknown position
PsiMod Name
O-fucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to an O-fucosylserine.
Cross References
RefSeq
NP_036577.1
,
NP_001185950.1
,
NP_001121797.1
OpenTargets
ENSG00000159674
HPA
ENSG00000159674-SPON2
GeneCards
Q9BUD6
Ensembl
ENST00000431380
,
ENSP00000483599
,
ENST00000617421
,
ENST00000290902
,
ENSG00000159674
,
ENSP00000394832
,
ENSP00000290902
PRO
Q9BUD6
Pharos - Targets
Q9BUD6
PDB
3D34
HMDB Protein
HMDBP13734
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