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CHRNB2 [plasma membrane]
Stable Identifier
R-HSA-507826
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Neuronal acetylcholine receptor subunit beta-2, ACHB2_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Acetylcholine binding and downstream events (Homo sapiens)
Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptor alpha4(2)-beta2(3) subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptor alpha4(2)-beta2(3) subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptor alpha4(2)-beta2(3) subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Presynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)
0-acteylcholine bound to calcium permeable nictonic acteylcholine receptor complex [plasma membrane] (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptors alpha4(3)-beta2(2) [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta2-aplha5 [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Homo sapiens)
0-acteylcholine bound to calcium permeable nictonic acteylcholine receptor complex [plasma membrane] (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptors alpha4(3)-beta2(2) [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta2-aplha5 [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptors alpha4(3)-beta2(2) [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta2-aplha5 [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptor alpha4(2)-beta2(3) subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptor alpha4(2)-beta2(3) subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine Receptor alpha4(2)-beta2(3) subunits [plasma membrane] (Homo sapiens)
CHRNB2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P17787 CHRNB2
Gene Names
CHRNB2
Chain
signal peptide:1-25, chain:26-502
Reference Genes
BioGPS Gene:1141 CHRNB2
COSMIC (genes):CHRNB2 CHRNB2
CTD Gene:1141 CHRNB2
dbSNP Gene:1141 CHRNB2
ENSEMBL:ENSG00000160716 CHRNB2
ENSEMBL_homo_sapiens_GENE:ENSG00000160716.6 CHRNB2
HGNC:1962 CHRNB2
KEGG Gene (Homo sapiens):1141 CHRNB2
Monarch:1141 CHRNB2
NCBI Gene:1141 CHRNB2
OMIM:118507 CHRNB2
Reference Transcript
RefSeq:NM_000748.2 CHRNB2
Other Identifiers
1141
11732598_at
11732599_at
11732600_at
16671494
206635_PM_at
206635_at
2360347
2360348
2360349
2360350
2360351
2360352
2360353
2360354
2360355
2360356
2360357
2360358
2360359
2360360
2360361
2360362
2360363
241389_PM_at
241389_at
34154_at
3634692
73294_at
73602_at
7905817
A_14_P108088
A_23_P368624
A_24_P388003
A_32_P77178
A_33_P3215635
GE80949
GO:0001666
GO:0002376
GO:0003012
GO:0003014
GO:0004888
GO:0005215
GO:0005216
GO:0005230
GO:0005515
GO:0005886
GO:0005892
GO:0006811
GO:0006816
GO:0006939
GO:0007154
GO:0007165
GO:0007271
GO:0007601
GO:0007605
GO:0007612
GO:0007613
GO:0007626
GO:0008306
GO:0008542
GO:0009897
GO:0014059
GO:0015276
GO:0015464
GO:0016020
GO:0019233
GO:0021562
GO:0021631
GO:0021771
GO:0021952
GO:0022848
GO:0023052
GO:0030154
GO:0030890
GO:0032225
GO:0032991
GO:0033603
GO:0034220
GO:0034330
GO:0035094
GO:0035095
GO:0035176
GO:0042053
GO:0042113
GO:0042166
GO:0042220
GO:0042320
GO:0042734
GO:0043005
GO:0043226
GO:0044853
GO:0044877
GO:0045202
GO:0045211
GO:0045471
GO:0045759
GO:0048814
GO:0048856
GO:0050877
GO:0050890
GO:0050997
GO:0051899
GO:0051963
GO:0055085
GO:0060078
GO:0060079
GO:0060084
GO:0060089
GO:0095500
GO:0097060
GO:0098981
GO:0099634
GO:1901363
GO:1904315
GO:1905144
HMNXSV003028967
Hs.225566.0.S1_3p_at
Hs.225566.0.S1_3p_x_at
ILMN_1676624
PH_hs_0000311
TC01001279.hg
U62437_at
g4502832_3p_at
Participates
as a member of
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
as a component of
Acetylcholine Receptor alpha4(2)-beta2(3) subunits [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta2-aplha5 [plasma membrane] (Homo sapiens)
Acetylcholine Receptors alpha4(3)-beta2(2) [plasma membrane] (Homo sapiens)
Inferred To
acr-12 [plasma membrane]
(Caenorhabditis elegans)
CHRNB2 [plasma membrane]
(Bos taurus)
CHRNB2 [plasma membrane]
(Canis familiaris)
CHRNB2 [plasma membrane]
(Gallus gallus)
CHRNB2 [plasma membrane]
(Sus scrofa)
unc-63 [plasma membrane]
(Caenorhabditis elegans)
acr-8 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CHRNB2 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CHRNB2 [plasma membrane]
(Drosophila melanogaster)
lev-1 [plasma membrane]
(Caenorhabditis elegans)
Chrnb2 [plasma membrane]
(Mus musculus)
Chrnb2 [plasma membrane]
(Rattus norvegicus)
nAChRalpha2 [plasma membrane]
(Drosophila melanogaster)
chrnb2 [plasma membrane]
(Xenopus tropicalis)
nAChRalpha3 [plasma membrane]
(Drosophila melanogaster)
unc-29 [plasma membrane]
(Caenorhabditis elegans)
acr-3 [plasma membrane]
(Caenorhabditis elegans)
nAChRalpha4 [plasma membrane]
(Drosophila melanogaster)
acr-6 [plasma membrane]
(Caenorhabditis elegans)
nAChRbeta2 [plasma membrane]
(Drosophila melanogaster)
acr-2 [plasma membrane]
(Caenorhabditis elegans)
lev-8 [plasma membrane]
(Caenorhabditis elegans)
nAChRalpha1 [plasma membrane]
(Drosophila melanogaster)
nAChRbeta1 [plasma membrane]
(Drosophila melanogaster)
unc-38 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_000739.1
Guide to Pharmacology - Targets
472
OpenTargets
ENSG00000160716
GeneCards
P17787
HPA
ENSG00000160716-CHRNB2
ZINC target
P17787
Ensembl
ENSG00000160716
,
ENST00000368476
,
ENSP00000357461
PRO
P17787
Pharos - Targets
P17787
Orphanet
17591
HMDB Protein
HMDBP12044
PDB
8ST2
,
2LM2
,
6UR8
,
8SSZ
,
8ST0
,
2K58
,
8ST3
,
2K59
,
2KSR
,
6CNK
,
6USF
,
5KXI
,
8ST1
,
8ST4
,
6CNJ
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