Reactome | MT-ATP6 [mitochondrial inner membrane]

MT-ATP6 [mitochondrial inner membrane]

Stable Identifier

R-HSA-50498

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATP synthase subunit a, Protein 6

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Organelle biogenesis and maintenance (Homo sapiens)

- Mitochondrial biogenesis (Homo sapiens)
  - Cristae formation (Homo sapiens)
    - F1Fo ATP synthase dimerizes (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        MT-ATP6 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase dimer [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        MT-ATP6 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P00846 MT-ATP6

Gene Names

MT-ATP6, ATP6, ATPASE6, MTATP6

Chain

chain:1-226

Reference Genes

BioGPS Gene:4508 MT-ATP6

COSMIC (genes):MT-ATP6 MT-ATP6

CTD Gene:4508 MT-ATP6

dbSNP Gene:4508 MT-ATP6

ENSEMBL:ENSG00000198899 MT-ATP6

HGNC:7414 MT-ATP6

KEGG:hsa:4508 MT-ATP6

Monarch:4508 MT-ATP6

NCBI Gene:4508 MT-ATP6

OMIM:516060 MT-ATP6

UCSC:P00846 MT-ATP6

Reference Transcript

RefSeq:NC_012920.1 MT-ATP6

Other Identifiers

11758423_s_at

11762922_s_at

11762923_x_at

1553567_3p_s_at

1553567_PM_s_at

1553567_s_at

1553588_PM_at

1553588_at

17100663

17100665

17100667

17100669

17126266

17126268

2315317

2315318

2315319

2492706

2492708

4037637

4037639

4037640

4037641

4037642

4037643

4037644

4037645

4037646

4037647

4037648

4037649

4037651

4037653

4508

7896752

8043375

8165667

8165669

8165672

8165674

A_23_P337726

A_23_P360209

A_33_P3410700

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0006754

GO:0015078

GO:0015986

GO:0016874

GO:0042776

GO:0043226

GO:0045259

GO:0045263

GO:0046933

GO:0055085

GO:0055086

GO:0055093

GO:1901135

GO:1902600

HMNXSV003008622

HMNXSV003022003

HMNXSV003041642

Hs2Affx.1.41.S1_3p_s_at

Hs2Affx.1.52.S1_3p_at

PH_hs_0033947

PH_hs_0036541

RNA143496|tRNA_413_70

TC01000013.hg

TC0M000005.hg

TC0M000006.hg

TC0M000022.hg

Participates

as a member of

Substrate of AFG3L2 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as a component of

ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)

Inferred To

MT-ATP6 [mitochondrial inner membrane] (Bos taurus)

MT-ATP6 [mitochondrial inner membrane] (Gallus gallus)

MT-ATP6 [mitochondrial inner membrane] (Sus scrofa)

Mtatp6 [mitochondrial inner membrane] (Mus musculus)

Mt-atp6 [mitochondrial inner membrane] (Rattus norvegicus)

atp6 [mitochondrial inner membrane] (Dictyostelium discoideum)

atp6 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

mt-atp6 [mitochondrial inner membrane] (Danio rerio)

mt-atp6 [mitochondrial inner membrane] (Xenopus tropicalis)

mt:ATPase6 [mitochondrial inner membrane] (Drosophila melanogaster)

Ghost homologue of MT-ATP6 [mitochondrial inner membrane] (Canis familiaris)

atp-6 [mitochondrial inner membrane] (Caenorhabditis elegans)

ATP6 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Cross References

Guide to Pharmacology - Targets

801

ENSEMBL

ENSP00000354632

OpenTargets

ENSG00000198899

HPA

ENSG00000198899-MT-ATP6

PRO

P00846

Pharos - Targets

P00846

GlyGen

P00846

Orphanet

MT-ATP6

PDB

8H9F, 8H9U, 8H9V, 8KI3, 8H9J, 8KHF, 8H9T, 8H9M, 8H9S, 8H9Q