RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1

Stable Identifier
R-HSA-4570493
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm, nuclear envelope
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RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1
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RANBP2 (NUP358) SUMOylates HNRNPC at lysine-237 of isoform C1 (lysine-250 of the reference isoform C2) with SUMO1 (Vassileva et al. 2004). SUMOylation decreases the interaction of HNRNPC with single-stranded DNA.

Literature References
PubMed ID Title Journal Year
15082759 SUMO modification of heterogeneous nuclear ribonucleoproteins

Vassileva, MT, Matunis, MJ

Mol. Cell. Biol. 2004
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Output
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as an event of
Catalyst Activity

SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope]

Physical Entity
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Danio rerio)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Mus musculus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Rattus norvegicus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Saccharomyces cerevisiae)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Schizosaccharomyces pombe)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Xenopus tropicalis)
Authored
May, B  (2013-09-19)
Reviewed
Filosa, G  (2015-10-17)
Bachi, A  (2015-10-17)
Created
May, B  (2013-09-21)
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