Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
HIST3H2A [nucleoplasm]
Stable Identifier
R-HSA-4549209
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone H2A type 3, H2A3_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
Histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
NuA4 complex acetylates histone H2A, HIST1H4 (Homo sapiens)
Histone H2A, HIST1H4 [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
HDACs deacetylate histones (Homo sapiens)
HDAC10 deacetylates histone (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
HDAC1:2-containing complex deacetylate histones (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
HDAC3 containing complexes deacetylate histone (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
HDAC8 deacetylates histones (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
RMTs methylate histone arginines (Homo sapiens)
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Homo sapiens)
MeR12-histone H2A, Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Homo sapiens)
MeR4-histone H2A, Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Homo sapiens)
MeR30-histone H2A, Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Early Events (Homo sapiens)
Activation of Latent HCMV Genome (Homo sapiens)
Latent Transcriptionally Repressed HCMV Genome [nucleoplasm] (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
Latent Transcriptinally Repressed HCMV Genome (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
Latent Transcriptionally Repressed HCMV Genome [nucleoplasm] (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Metalloprotease DUBs (Homo sapiens)
BRCA1-A complex deubiquitinates K63polyUb-histone H2A (Homo sapiens)
BRCA1-A Complex:Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
MYSM1 deubiquitinates Histone H2A (Homo sapiens)
MYSM1:EP300:KAT2B:Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
UCH proteinases (Homo sapiens)
Histone H2A is dubiquitinated by the PR-DUB complex (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP16,USP21 deubiquitinate Histone H2A (Homo sapiens)
USP16,USP22:Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
HIST3H2A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7L7L0 H2AC25
Gene Names
H2AC25, H2AW, HIST3H2A
Chain
initiator methionine:, chain:2-130
Reference Genes
BioGPS Gene:92815 H2AC25
COSMIC (genes):HIST3H2A H2AC25
CTD Gene:92815 H2AC25
dbSNP Gene:92815 H2AC25
ENSEMBL:ENSG00000181218 HIST3H2A
HGNC:20507 H2AC25
KEGG:hsa:92815 H2AC25
Monarch:92815 H2AC25
NCBI Gene:92815 H2AC25
OMIM:615015 H2AC25
UCSC:Q7L7L0 H2AC25
Reference Transcript
RefSeq:NM_033445.2 H2AC25
Other Identifiers
11758356_s_at
16700236
16700239
221582_PM_at
221582_at
2459525
2459617
2459618
2459619
2459620
52855_at
7924888
92815
ADDON002760.hg
A_21_P0001637
A_23_P149301
A_33_P3404032
GE83647
GO:0000786
GO:0003677
GO:0005198
GO:0005515
GO:0005634
GO:0005694
GO:0006281
GO:0006325
GO:0006337
GO:0030527
GO:0031492
GO:0031507
GO:0043226
GO:0043229
GO:0046982
GO:0070062
GO:0070914
HMNXSV003011645
HMNXSV003054421
ILMN_1779648
PH_hs_0032764
TC01003916.hg
TC01006171.hg
g12654706_3p_at
p17575
Participates
as a candidate of
Histone H2A [nucleoplasm] (Homo sapiens)
Other forms of this molecule
AcK-HIST3H2A [nucleoplasm]
MeR12-HIST3H2A [nucleoplasm]
Me2aR12-HIST3H2A [nucleoplasm]
MeR4-HIST3H2A [nucleoplasm]
Me2aR4-HIST3H2A [nucleoplasm]
MeR30-HIST3H2A [nucleoplasm]
Me2aR30-HIST3H2A [nucleoplasm]
AcK6-HIST3H2A [nucleoplasm]
Ub-HIST3H2A [nucleoplasm]
K63polyUb-HIST3H2A [nucleoplasm]
Inferred To
LOC100485548 [nucleoplasm]
(Xenopus tropicalis)
LOC100487632 [nucleoplasm]
(Xenopus tropicalis)
LOC116411633 [nucleoplasm]
(Xenopus tropicalis)
his-35 [nucleoplasm]
(Caenorhabditis elegans)
HTA1 [nucleoplasm]
(Saccharomyces cerevisiae)
HTA2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Av2 [nucleoplasm]
(Dictyostelium discoideum)
His2A:CG33862 [nucleoplasm]
(Drosophila melanogaster)
hta1 [nucleoplasm]
(Schizosaccharomyces pombe)
histone H2A type3 [nucleoplasm]
(Rattus norvegicus)
his-65 [nucleoplasm]
(Caenorhabditis elegans)
hta2 [nucleoplasm]
(Schizosaccharomyces pombe)
h2ac16 [nucleoplasm]
(Xenopus tropicalis)
HIST1H2AB [nucleoplasm]
(Gallus gallus)
HIST1H2AB [nucleoplasm]
(Plasmodium falciparum)
H2AC25 [nucleoplasm]
(Bos taurus)
H2AC25 [nucleoplasm]
(Canis familiaris)
H2AC25 [nucleoplasm]
(Sus scrofa)
LOC116407737 [nucleoplasm]
(Xenopus tropicalis)
LOC100487067 [nucleoplasm]
(Xenopus tropicalis)
h2ax1 [nucleoplasm]
(Danio rerio)
Homologues of HIST1H2AB [nucleoplasm]
(Caenorhabditis elegans)
Homologues of HIST1H2AB [nucleoplasm]
(Danio rerio)
Homologues of HIST1H2AB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of HIST1H2AB [nucleoplasm]
(Drosophila melanogaster)
Homologues of HIST1H2AB [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of HIST1H2AB [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of HIST1H2AB [nucleoplasm]
(Xenopus tropicalis)
zgc:56685 [nucleoplasm]
(Danio rerio)
H2AX [nucleoplasm]
(Dictyostelium discoideum)
H2Av3 [nucleoplasm]
(Dictyostelium discoideum)
htas-1 [nucleoplasm]
(Caenorhabditis elegans)
H2Av1 [nucleoplasm]
(Dictyostelium discoideum)
Histone H2A type 3 [nucleoplasm]
(Mus musculus)
LOC101732059 [nucleoplasm]
(Xenopus tropicalis)
His2A:CG33859 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_254280.1
OpenTargets
ENSG00000181218
ENSEMBL
ENST00000645741
,
ENSP00000355656
,
ENST00000366695
,
ENSP00000510421
,
ENSP00000493926
,
ENST00000691624
,
ENST00000689584
,
ENSP00000508783
HPA
ENSG00000181218-H2AC25
PRO
Q7L7L0
Pharos - Targets
Q7L7L0
GlyGen
Q7L7L0
HMDB Protein
HMDBP07731
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19404 NDUFV2
1
NDUFV2 [mitochondrial inner membrane]
(R-HSA-163939)
0.556
3
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text