Phosphorylation of IL2RB Y338 creates a binding site for the accessory protein SHC, which then becomes tyrosine phosphorylated and recruits the Grb2/Sos and Grb2:Gab2 complexes.
Friedmann, MC, Migone, TS, Russell, SM, Leonard, WJ
Ravichandran, KS, Igras, V, Shoelson, SE, Fesik, SW, Burakoff, SJ
Evans, GA, Goldsmith, MA, Johnston, JA, Xu, W, Weiler, SR, Erwin, R, Howard, OM, Abraham, RT, O'Shea, JJ, Greene, WC
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