Reactome | IL20RA binds IL20RB

IL20RA binds IL20RB

Stable Identifier

R-HSA-448744

Type

Reaction [uncertain]

Species

Homo sapiens

Compartment

plasma membrane, cytosol

ReviewStatus

5/5

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Interleukin-20 receptor A (IL20RA) binds to Interleukin-20 receptor B (IL20RB) (Blumberg et al. 2001, Parrish-Novak et al. 2002, Logsdon et al. 2012, Rutz et al. 2014, Dumoutier et al. 2001).
This is a black box event because it is not clear whether the dimeric receptor can form in the absence of ligand.

Literature References

PubMed ID	Title	Journal	Year
11163236	Interleukin 20: discovery, receptor identification, and role in epidermal function Sexson, S, Parrish-Novak, J, Dale, BA, Xu, WF, Eagan, M, Yao, L, Madden, K, Carollo, S, Prunkard, D, Kuechle, MK, Whitmore, TE, Kelly, JD, Hammond, A, Blumberg, H, Foster, D, Sprecher, C, Chandrasekher, YA, Jelinek, L, Brender, T, Grossmann, A, Conklin, D, Haugen, H, West, J, Haldeman, BA, Waggie, K, Maurer, MF	Cell	2001
11564763	Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types Renauld, JC, Kotenko, SV, Leemans, C, Dumoutier, L, Lejeune, D	J Immunol	2001