ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP

Stable Identifier
R-HSA-446207
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Addition of the second N-acetyl-glucosamine to the N-glycan precursor
Locations in the PathwayBrowser
General
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A second N-acetylglucosamine is added to the N-glycan precursor via a beta-1,4 linkage. This reaction is catalyzed by the ALG13:ALG14 complex, in which ALG13 functions as the catalyst and ALG14 functions as a membrane anchor which recruits ALG13 to the cytosolic face of ER (Gao XD et al, 2005).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity of ALG13:ALG14 [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created