A second N-acetylglucosamine is added to the N-glycan precursor via a beta-1,4 linkage. This reaction is catalyzed by the ALG13:ALG14 complex, in which ALG13 functions as the catalyst and ALG14 functions as a membrane anchor which recruits ALG13 to the cytosolic face of ER (Gao XD et al, 2005).
Tachikawa, H, Gao, XD, Sato, T, Dean, N, Jigami, Y
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity of ALG13:ALG14 [endoplasmic reticulum membrane]
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