Reactome | Phosphorylation of Smooth Muscle Myosin Light Chains

Phosphorylation of Smooth Muscle Myosin Light Chains

Stable Identifier

R-HSA-445813

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Phosphorylation of Smooth Muscle Myosin Light Chains

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The smooth muscle light chain kinase phosphorylates the smooth muscle light chains. This phosphorylation activates the myosin lights chains, effectively allowing contraction to begin.

Literature References

PubMed ID	Title	Journal	Year
2526655	Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells Kumar, CC, Mohan, SR, Zavodny, PJ, Narula, SK, Leibowitz, PJ	Biochemistry	1989
3780718	Isoforms of myosin and actin in human, monkey and rat myometrium. Comparison of pregnant and non-pregnant uterus proteins Cavaillé, F, Janmot, C, Ropert, S, d'Albis, A	Eur J Biochem	1986
2764880	The distribution of heavy-chain isoforms of myosin in airways smooth muscle from adult and neonate humans Mohammad, MA, Sparrow, MP	Biochem J	1989