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Reinsertion of L1 into the plasma membrane
Stable Identifier
R-HSA-445071
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol
,
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Recycling pathway of L1 (Homo sapiens)
Reinsertion of L1 into the plasma membrane (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
L1 transported to the P-domain of growth cones is reinserted into the plasma membrane at the leading edge.
Literature References
PubMed ID
Title
Journal
Year
10804209
Recycling of the cell adhesion molecule L1 in axonal growth cones
Kamiguchi, H
,
Lemmon, V
J Neurosci
2000
10747093
Evidence for the involvement of KIF4 in the anterograde transport of L1-containing vesicles
Peretti, D
,
Caceres, A
,
Quiroga, S
,
Peris, L
,
Rosso, S
J Cell Biol
2000
Participants
Input
AP2 clathrin:L1:KIF4:microtubule [cytosol]
(Homo sapiens)
Output
Clathrin:AP-2 complex [plasma membrane]
(Homo sapiens)
KIF4 dimer [cytosol]
(Homo sapiens)
L1CAM [plasma membrane]
(Homo sapiens)
Microtubule [cytosol]
(Homo sapiens)
SH3GL2 [plasma membrane]
(Homo sapiens)
Participates
as an event of
Recycling pathway of L1 (Homo sapiens)
Orthologous Events
Reinsertion of L1 into the plasma membrane (Mus musculus)
Reinsertion of L1 into the plasma membrane (Rattus norvegicus)
Reinsertion of L1 into the plasma membrane (Xenopus tropicalis)
Authored
Garapati, P V (2008-07-30)
Reviewed
Maness, PF (2010-02-16)
Created
Garapati, P V (2009-10-27)
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