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PROKR1 [plasma membrane]
Stable Identifier
R-HSA-444668
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Prokineticin receptor 1, PKR1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Prokineticin receptors bind prokineticin (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Homo sapiens)
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
PROKR1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TCW9 PROKR1
Gene Names
PROKR1, GPR73, PKR1
Chain
chain:1-393
Reference Genes
BioGPS Gene:10887 PROKR1
COSMIC (genes):PROKR1 PROKR1
CTD Gene:10887 PROKR1
dbSNP Gene:10887 PROKR1
ENSEMBL:ENSG00000169618 PROKR1
ENSEMBL_homo_sapiens_GENE:ENSG00000169618.7 PROKR1
HGNC:4524 PROKR1
KEGG Gene (Homo sapiens):10887 PROKR1
Monarch:10887 PROKR1
NCBI Gene:10887 PROKR1
OMIM:607122 PROKR1
UCSC:Q8TCW9 PROKR1
Reference Transcript
RefSeq:NM_138964.3 PROKR1
Other Identifiers
10887
11732973_at
16880977
2486909
2486910
2486911
2486912
2486915
2486916
2486917
2486918
2486919
2486920
2486921
2486922
8042413
ADDON002759.hg
A_14_P121174
A_23_P416089
A_33_P3236724
GO:0004930
GO:0004983
GO:0005886
GO:0007165
GO:0007186
GO:0007218
GO:0007623
GO:0016020
GO:0023052
GO:0060089
HMNXSV003050231
ILMN_1704751
PH_hs_0017517
TC02004968.hg
Participates
as a member of
PROKR1,PROKR2 [plasma membrane] (Homo sapiens)
Inferred To
TrissinR [plasma membrane]
(Drosophila melanogaster)
Homologues of PROKR1 [plasma membrane]
(Danio rerio)
PROKR1 [plasma membrane]
(Canis familiaris)
PROKR1 [plasma membrane]
(Gallus gallus)
PROKR1 [plasma membrane]
(Sus scrofa)
si:ch211-44l19.2 [plasma membrane]
(Danio rerio)
prokr1l [plasma membrane]
(Danio rerio)
pcdr-1 [plasma membrane]
(Caenorhabditis elegans)
Prokr1 [plasma membrane]
(Mus musculus)
Prokr1 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_620414.1
Guide to Pharmacology - Targets
335
OpenTargets
ENSG00000169618
GeneCards
Q8TCW9
ZINC - Substances
PKR1_HUMAN
HPA
ENSG00000169618-PROKR1
ZINC target
Q8TCW9
Ensembl
ENSP00000303775
,
ENSG00000169618
,
ENST00000303786
PRO
Q8TCW9
Pharos - Targets
Q8TCW9
ZINC - Predictions - Purchasable
PKR1_HUMAN
HMDB Protein
HMDBP07943
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