Choline (Cho) transports from the extracellular space through the plasma membrane via the choline transporter-like proteins (SLC44A1-5 also known as CTL1-5) to the cytosol (Okuda & Haga 2000, Traiffort et al. 2005, O'Regan et al. 2000).CTL1 is broadly expressed on leukocytes and endothelial cells (Wille et al. 2001). CTL2 is highly expressed in human inner ear and is the target of antibody-induced hearing loss (Nair et al. 2004).
Haga, T, Okuda, T
Wille, S, Knapp, W, Prieschl, EE, Staffler, G, Stockinger, H, Stockl, J, Szekeres, A, Majdic, O, Prager, E, Burtscher, H, Kunthalert, D, Baumruker, T, Zlabinger, GJ
O'Regan, S, Meunier, FM, Ruat, M, Traiffort, E
Compaore, D, Cha, N, O'Regan, S, Meunier, FM, Ruat, M, Traiffort, E
Lansford, CD, Lomax, MI, Gong, TW, Carey, TE, Kozma, KE, Raphael, Y, El-Kashlan, HK, Kommareddi, PK, Berryhill, WE, Satar, B, Ueda, Y, Nair, TS, Arts, HA, Hoefling, NL, Telian, SA
choline transmembrane transporter activity of CTL1-5 [plasma membrane]
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