NACT co-transports trivalent citrate and a sodium ion

Stable Identifier
R-HSA-433104
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The human SLC13A5 gene encodes a sodium-coupled citrate transporter, NACT. This gene is expressed mainly in the liver, with lower levels in brain and testis. NACT has a preference for trivalent citrate (Inoue K et al, 2002).

Literature References
PubMed ID Title Journal Year
12445824 Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function

Inoue, K, Zhuang, L, Ganapathy, V

Biochem Biophys Res Commun 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
citrate transmembrane transporter activity of SLC13A5 [plasma membrane]
Physical Entity
Activity
Orthologous Events
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