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PPM1L [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-429688
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
protein phosphatase 1-like
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Sphingolipid de novo biosynthesis (Homo sapiens)
CERT1-2 complex binds ceramide (Homo sapiens)
CERT1-2:PPM1L:VAPA/B trimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
ceramide:CERT1-2:PPM1L:VAPA/B trimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
CERT1-2 complex dissociates (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
ceramide:CERT1-2:PPM1L:VAPA/B trimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
Multiphospho-CERT1-2 binds PPM1L, VAPA/B (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
p-S,S132,T-CERT1-2:PPM1L:VAPA/B trimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L dephosphorylates multiphospho-CERT1-2 (Homo sapiens)
CERT1-2:PPM1L:VAPA/B trimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
p-S,S132,T-CERT1-2:PPM1L:VAPA/B trimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
PPM1L [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5SGD2 PPM1L
Gene Names
PPM1L, PP2CE
Chain
chain:1-360
Reference Genes
BioGPS Gene:151742 PPM1L
COSMIC (genes):PPM1L PPM1L
CTD Gene:151742 PPM1L
dbSNP Gene:151742 PPM1L
ENSEMBL:ENSG00000163590 PPM1L
ENSEMBL_homo_sapiens_GENE:ENSG00000163590.14 PPM1L
HGNC:16381 PPM1L
KEGG Gene (Homo sapiens):151742 PPM1L
Monarch:151742 PPM1L
NCBI Gene:151742 PPM1L
OMIM:611931 PPM1L
UCSC:Q5SGD2 PPM1L
Reference Transcript
RefSeq:NM_001317912.1 PPM1L
RefSeq:NM_001317911.1 PPM1L
RefSeq:NM_139245.3 PPM1L
Other Identifiers
11738104_a_at
11756821_a_at
151742
228108_PM_at
228108_at
228457_PM_at
228457_at
229506_PM_at
229506_at
236339_PM_at
236339_at
239488_PM_at
239488_at
2650392
2650394
2650395
2650396
2650397
2650413
2650428
2650432
2650433
2650463
2650465
2650466
2650467
2650468
2650473
2650474
2650476
2650478
2650480
2650481
2650482
2650483
2650485
2650487
2650489
2650490
2650492
53258_at
57656_at
59136_at
59452_at
71667_at
8083749
A_23_P147563
A_32_P429876
GE52965
GE85873
GO:0000165
GO:0003824
GO:0004721
GO:0004722
GO:0005576
GO:0005615
GO:0005783
GO:0005789
GO:0006470
GO:0006629
GO:0007178
GO:0016020
GO:0016787
GO:0017018
GO:0023052
GO:0030148
GO:0036211
GO:0043169
GO:0043226
GO:0046872
GO:0070062
GO:0140096
HMNXSV003047870
Hs.12731.0.A1_3p_at
Hs.19339.0.A1_3p_at
Hs.221001.0.A1_3p_at
Hs.28068.0.A1_3p_at
Hs.285293.0.A1_3p_at
ILMN_1763793
PH_hs_0001702
PH_hs_0023783
TC03002632.hg
p26241
Participates
as a component of
PPM1L:VAPA/B dimer [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
Dmel\CG7115 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ppm1l [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Ppm1l [endoplasmic reticulum membrane]
(Rattus norvegicus)
ppm1la [endoplasmic reticulum membrane]
(Danio rerio)
PPM1L [endoplasmic reticulum membrane]
(Bos taurus)
PPM1L [endoplasmic reticulum membrane]
(Canis familiaris)
PPM1L [endoplasmic reticulum membrane]
(Mus musculus)
PPM1L [endoplasmic reticulum membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001304841.1
,
NP_640338.2
,
NP_001304840.1
OpenTargets
ENSG00000163590
GeneCards
Q5SGD2
HPA
ENSG00000163590-PPM1L
Ensembl
ENSP00000420746
,
ENST00000497343
,
ENST00000498165
,
ENSP00000417659
,
ENSP00000420354
,
ENST00000464260
,
ENSP00000295839
,
ENST00000295839
,
ENSG00000163590
PRO
Q5SGD2
Pharos - Targets
Q5SGD2
HMDB Protein
HMDBP08799
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