Transcription of intergenic spacer of the rRNA gene

Stable Identifier
R-HSA-427366
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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As inferred from mouse cell models, intergenic spacer regions (IGS) located between rRNA transcription units contain upstream promoters and are transcribed by RNA Polymerase I. The IGS transcripts originate approximately 2 Kb upstream of the start of rRNA transcription and proceed though the main promoter of the rRNA gene.

Literature References
PubMed ID Title Journal Year
19838300 An intergenic non-coding rRNA correlated with expression of the rRNA and frequency of an rRNA single nucleotide polymorphism in lung cancer cells

Shiao, YH, Lupascu, ST, Gu, YD, Kasprzak, W, Hwang, CJ, Fields, JR, Leighty, RM, QuiƱones, O, Shapiro, BA, Alvord, WG, Anderson, LM

PLoS One 2009
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Participant Of
Catalyst Activity
Catalyst Activity
Title
DNA-directed 5'-3' RNA polymerase activity of RNA Polymerase I promoter escape complex [nucleoplasm]
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Activity
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