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SLC8A3 [plasma membrane]
Stable Identifier
R-HSA-425658
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sodium/calcium exchanger 3, NAC3_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Platelet calcium homeostasis (Homo sapiens)
Reduction of cytosolic Ca++ levels (Homo sapiens)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
SLC8A1,2,3 [plasma membrane] (Homo sapiens)
SLC8A3 [plasma membrane] (Homo sapiens)
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
SLC8A1,2,3 [plasma membrane] (Homo sapiens)
SLC8A3 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Sodium/Calcium exchangers (Homo sapiens)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
SLC8A1,2,3 [plasma membrane] (Homo sapiens)
SLC8A3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P57103 SLC8A3
Gene Names
SLC8A3, NCX3
Chain
signal peptide:1-30, chain:31-927
Reference Genes
BioGPS Gene:6547 SLC8A3
COSMIC (genes):SLC8A3 SLC8A3
CTD Gene:6547 SLC8A3
dbSNP Gene:6547 SLC8A3
ENSEMBL:ENSG00000100678 SLC8A3
HGNC:11070 SLC8A3
KEGG:hsa:6547 SLC8A3
Monarch:6547 SLC8A3
NCBI Gene:6547 SLC8A3
OMIM:607991 SLC8A3
UCSC:P57103 SLC8A3
Reference Transcript
RefSeq:NM_182936.2 SLC8A3
RefSeq:XM_017021608.1 SLC8A3
RefSeq:NM_058240.3 SLC8A3
RefSeq:NM_182932.2 SLC8A3
RefSeq:NM_033262.4 SLC8A3
RefSeq:XM_017021606.1 SLC8A3
RefSeq:NM_001130417.2 SLC8A3
RefSeq:NM_183002.2 SLC8A3
Other Identifiers
11729872_a_at
1562403_PM_a_at
1562403_a_at
1568859_PM_a_at
1568859_a_at
16794278
3570370
3570372
3570374
3570375
3570376
3570377
3570378
3570379
3570380
3570381
3570382
3570384
3570385
3570386
3570387
3570388
3570391
3570399
3570412
3570413
3570416
3570417
3570418
6547
7979888
83364_at
A_23_P48487
A_24_P167654
GE83635
GO:0002244
GO:0005215
GO:0005432
GO:0005515
GO:0005516
GO:0005737
GO:0005739
GO:0005741
GO:0005783
GO:0005789
GO:0005886
GO:0006811
GO:0006814
GO:0006816
GO:0006851
GO:0006874
GO:0007154
GO:0007611
GO:0007612
GO:0007613
GO:0014069
GO:0014819
GO:0015297
GO:0015368
GO:0016020
GO:0016528
GO:0030001
GO:0030054
GO:0030154
GO:0030424
GO:0030425
GO:0031594
GO:0034330
GO:0035725
GO:0042383
GO:0042552
GO:0042995
GO:0043025
GO:0043197
GO:0043204
GO:0043226
GO:0043679
GO:0045202
GO:0046872
GO:0048471
GO:0048709
GO:0050808
GO:0050877
GO:0051560
GO:0055085
GO:0060291
GO:0070161
GO:0070588
GO:0071456
GO:0071901
GO:0098703
GO:0098794
GO:0098815
GO:1903779
HMNXSV003029719
Hs2.337696.3.S1_3p_a_at
Hs2.337696.4.S1_3p_a_at
ILMN_1696056
ILMN_1712023
ILMN_1770987
PH_hs_0026819
TC14001265.hg
X93017_at
Participates
as a member of
SLC8A1,2,3 [plasma membrane] (Homo sapiens)
Other forms of this molecule
SLC8A3 [mitochondrial outer membrane]
Inferred To
Homologues of SLC8A3 [plasma membrane]
(Caenorhabditis elegans)
COX16 [plasma membrane]
(Gallus gallus)
ncx-1 [plasma membrane]
(Caenorhabditis elegans)
slc8a3 [plasma membrane]
(Xenopus tropicalis)
ncx-2 [plasma membrane]
(Caenorhabditis elegans)
SLC8A3 [plasma membrane]
(Bos taurus)
SLC8A3 [plasma membrane]
(Canis familiaris)
SLC8A3 [plasma membrane]
(Drosophila melanogaster)
SLC8A3 [plasma membrane]
(Mus musculus)
SLC8A3 [plasma membrane]
(Rattus norvegicus)
SLC8A3 [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
947
ENSEMBL
ENST00000356921
,
ENST00000394330
,
ENSP00000370669
,
ENST00000705391
,
ENST00000216568
,
ENSP00000216568
,
ENST00000494208
,
ENSP00000436332
,
ENSP00000377863
,
ENST00000534137
,
ENSP00000516120
,
ENST00000528359
,
ENST00000381269
,
ENSP00000349392
,
ENSP00000436688
,
ENSP00000433531
OpenTargets
ENSG00000100678
HPA
ENSG00000100678-SLC8A3
PRO
P57103
Pharos - Targets
P57103
GlyGen
P57103
HMDB Protein
HMDBP03168
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