Reactome | ADM(95-146) [extracellular region]

ADM(95-146) [extracellular region]

Stable Identifier

R-HSA-420093

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Adrenomedullin, ADM, ADML_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P35318 ADM

Gene Names

ADM, AM

Chain

signal peptide:1-21, peptide:22-41, propeptide:45-92, peptide:95-146, propeptide:148-185

Reference Genes

BioGPS Gene:133 ADM

COSMIC (genes):ADM ADM

CTD Gene:133 ADM

dbSNP Gene:133 ADM

ENSEMBL:ENSG00000148926 ADM

HGNC:259 ADM

KEGG:hsa:133 ADM

Monarch:133 ADM

NCBI Gene:133 ADM

OMIM:103275 ADM

UCSC:P35318 ADM

Reference Transcript

RefSeq:NM_001124.2 ADM

Other Identifiers

11716710_a_at

11753618_a_at

11756406_x_at

133

16721905

202912_PM_at

202912_at

3320128

3320129

3320130

3320131

3320132

3320133

3320134

3320135

3320136

3320137

3320138

3320139

3320140

3320141

34777_at

7938390

A_14_P117900

A_14_P120133

A_14_P130211

A_23_P127948

D14874_at

GE57093

GE85302

GO:0001570

GO:0001666

GO:0001843

GO:0002026

GO:0002031

GO:0003013

GO:0003014

GO:0003073

GO:0005102

GO:0005179

GO:0005576

GO:0005615

GO:0005737

GO:0006629

GO:0006954

GO:0007165

GO:0007189

GO:0007204

GO:0007507

GO:0007565

GO:0008209

GO:0008283

GO:0008284

GO:0008285

GO:0010460

GO:0016192

GO:0019933

GO:0022414

GO:0030154

GO:0031100

GO:0031102

GO:0031623

GO:0031700

GO:0032496

GO:0032868

GO:0035809

GO:0042475

GO:0042594

GO:0043065

GO:0043116

GO:0045472

GO:0045766

GO:0045906

GO:0048018

GO:0048589

GO:0048856

GO:0051384

GO:0060670

GO:0060712

GO:0097084

GO:0098772

GO:1990410

GO:2000184

GO:2001214

HMNXSV003011224

ILMN_1708934

PH_hs_0025829

TC11000182.hg

g4501944_3p_at

Participates

as an output of

Secretion of ADM (Adrenomedullin) (Homo sapiens)

as an input of

ADM (Adrenomedullin) binds CALCRL:RAMP2 (Homo sapiens)

as a component of

ADM:CALCRL:RAMP2 [plasma membrane] (Homo sapiens)

as a member of

ADM,ADM2 [extracellular region] (Homo sapiens)

Other forms of this molecule

ADM(95-146) [secretory granule lumen]

Inferred To

Adm [extracellular region] (Mus musculus)

Adm [extracellular region] (Rattus norvegicus)

adm [extracellular region] (Xenopus tropicalis)

ADM [extracellular region] (Bos taurus)

ADM [extracellular region] (Canis familiaris)

ADM [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_001115.1

ENSEMBL

ENST00000525063, ENST00000528655, ENSP00000435124, ENSP00000278175, ENSP00000436607, ENST00000278175

OpenTargets

ENSG00000148926

HPA

ENSG00000148926-ADM

PRO

P35318

Pharos - Targets

P35318

GlyGen

P35318

HMDB Protein

HMDBP02753

PDB

4RWF, 6UUS, 2L7S, 2FLY, 7VV0, 6UUN, 6V2E, 5V6Y

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