Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
RAMP1 [plasma membrane]
Stable Identifier
R-HSA-419763
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Receptor activity-modifying protein 1, RAMP1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AMY1-3:IAPP(34-70) [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP1 receptor:CGRP [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AMY1-3:IAPP(34-70) [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP1 receptor:CGRP [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AMY1-3:IAPP(34-70) [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP1 receptor:CGRP [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AMY1-3:IAPP(34-70) [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP1 receptor:CGRP [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AMY1-3:IAPP(34-70) [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP1 receptor:CGRP [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Calcitonin-like ligand receptors (Homo sapiens)
AMY1-3 bind IAPP(34-70) (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
AMY1-3:IAPP(34-70) [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
AMY1-3 bind pramlintide (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
AMY1-3:pramlintide [plasma membrane] (Homo sapiens)
AMY1-3 [plasma membrane] (Homo sapiens)
AMY1 receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP receptor can bind calcitonin gene-related peptides (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
CGRP1 receptor:CGRP [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
RAMP1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60894 RAMP1
Gene Names
RAMP1
Chain
signal peptide:1-26, chain:27-148
Reference Genes
BioGPS Gene:10267 RAMP1
COSMIC (genes):RAMP1 RAMP1
CTD Gene:10267 RAMP1
dbSNP Gene:10267 RAMP1
ENSEMBL:ENSG00000132329 RAMP1
ENSEMBL_homo_sapiens_GENE:ENSG00000132329.11 RAMP1
HGNC:9843 RAMP1
KEGG Gene (Homo sapiens):10267 RAMP1
Monarch:10267 RAMP1
NCBI Gene:10267 RAMP1
OMIM:605153 RAMP1
UCSC:O60894 RAMP1
Reference Transcript
RefSeq:NM_005855.3 RAMP1
Other Identifiers
10267
11721304_at
16892975
204916_PM_at
204916_at
2534513
2534514
2534515
2534523
2534539
2534540
2534541
35668_at
8049567
A_14_P108624
A_23_P50946
A_33_P3233906
GE55135
GO:0001525
GO:0001635
GO:0005515
GO:0005886
GO:0006486
GO:0006816
GO:0006886
GO:0007186
GO:0007189
GO:0008277
GO:0009986
GO:0015026
GO:0015031
GO:0016020
GO:0016192
GO:0023052
GO:0031623
GO:0032870
GO:0036211
GO:0043235
GO:0048856
GO:0060050
GO:0060089
GO:0072659
GO:0097643
GO:0097647
GO:1901135
GO:1990406
GO:1990407
GO:1990408
HMNXSV003005525
ILMN_1764754
PH_hs_0002780
TC02001447.hg
g5032018_3p_at
Participates
as a component of
AMY1 receptor [plasma membrane] (Homo sapiens)
CGRP receptor [plasma membrane] (Homo sapiens)
Inferred To
ramp1 [plasma membrane]
(Danio rerio)
ramp1 [plasma membrane]
(Xenopus tropicalis)
RAMP1 [plasma membrane]
(Bos taurus)
RAMP1 [plasma membrane]
(Canis familiaris)
RAMP1 [plasma membrane]
(Gallus gallus)
RAMP1 [plasma membrane]
(Sus scrofa)
Ramp1 [plasma membrane]
(Mus musculus)
Ramp1 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_005846.1
OpenTargets
ENSG00000132329
GeneCards
O60894
HPA
ENSG00000132329-RAMP1
Ensembl
ENST00000254661
,
ENSG00000132329
,
ENSP00000254661
PRO
O60894
Pharos - Targets
O60894
HMDB Protein
HMDBP12705
PDB
3N7P
,
7KNU
,
7TYF
,
7P0I
,
6ZHO
,
6D1U
,
6UMG
,
6ZIS
,
8AX5
,
8AX6
,
3N7S
,
8AX7
,
2YX8
,
7TYW
,
4RWG
,
3N7R
,
5V6Y
,
7P0F
,
6E3Y
,
7KNT
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text