p120-RasGAP (RASA1) binds to activated Ras (Ras:GTP) through its GAP-related catalytic domain, which is sufficient for stimulating the Ras GTPase activity. p120-RasGAP accelerates the intrinsic GTPase activity of Ras to promote Ras inactivation (Yao et al. 1995).
Cooper, GM, Yao, R
DeClue, JE, McCormick, F, Zhang, K, Lowy, DR, Papageorge, AG, Vass, WC
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