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Collagen type VII binds collagen type IV
Stable Identifier
R-HSA-4084501
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Extracellular matrix organization (Homo sapiens)
Laminin interactions (Homo sapiens)
Collagen type VII binds collagen type IV (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The NC1 domain of collagen VII is able to bind collagen type IV and laminin-322 (laminin-5) (Brittingham et al. 2006). This facilitates stabilization of the basement membrane structure.
Participants
Input
Collagen IV [extracellular region]
(Homo sapiens)
Collagen type VII fibril [extracellular region]
(Homo sapiens)
Output
Collagen type IV networks:Collagen type VII fibril [extracellular region]
(Homo sapiens)
Participates
as an event of
Laminin interactions (Homo sapiens)
Inferred From
Collagen VII binds collagen IV (Homo sapiens)
Authored
Jupe, S (2012-08-08)
Reviewed
Humphries, MJ (2008-05-07)
Yamada, KM (2008-05-07)
Hynes, R (2008-05-07)
Ricard-Blum, S (2013-08-13)
Created
Jupe, S (2013-07-29)
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