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GUCY1B3 [cytosol]
Stable Identifier
R-HSA-391995
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Guanylate cyclase soluble subunit beta-1, GCYB1_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Nitric oxide stimulates guanylate cyclase (Homo sapiens)
NO binds to Guanylate Cyclase (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
Soluble guanylate cyclase converts GTP to cGMP (Homo sapiens)
Guanylate cyclase:CO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
Muscle contraction (Homo sapiens)
Smooth Muscle Contraction (Homo sapiens)
Cinaciguat binds sGC:NO (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
NO binds to Guanylate Cyclase (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
Soluble guanylate cyclase converts GTP to cGMP (Homo sapiens)
Guanylate cyclase:CO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
sGC stimulators bind sGC:NO (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
GUCY1B3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02153 GUCY1B3
Gene Names
GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Chain
chain:1-619
Reference Genes
BioGPS Gene:2983 GUCY1B3
COSMIC (genes):GUCY1B1 GUCY1B3
CTD Gene:2983 GUCY1B3
dbSNP Gene:2983 GUCY1B3
ENSEMBL:ENSG00000061918 GUCY1B3
HGNC:4687 GUCY1B3
Monarch:2983 GUCY1B3
NCBI Gene:2983 GUCY1B3
OMIM:139397 GUCY1B3
UCSC:Q02153 GUCY1B3
Reference Transcript
RefSeq:NM_001291954.1 GUCY1B3
RefSeq:NM_001291953.1 GUCY1B3
RefSeq:NM_000857.3 GUCY1B3
RefSeq:NM_001291952.1 GUCY1B3
Other Identifiers
11726581_a_at
11745987_a_at
16971737
203817_PM_at
203817_at
211555_PM_s_at
211555_s_at
2748922
2748924
2748925
2748927
2748928
2748929
2748931
2748932
2748941
2748942
2748949
2748953
2748955
2748956
2748958
2748961
2748962
2748963
2748965
2748966
2748969
2748971
2748974
2748975
2748976
2748986
2748993
2983
37243_at
8097973
A_14_P116286
A_23_P121564
A_33_P3232552
GE59929
GO:0003013
GO:0003824
GO:0004016
GO:0004383
GO:0005515
GO:0005525
GO:0005737
GO:0005829
GO:0006182
GO:0007263
GO:0008015
GO:0008074
GO:0009190
GO:0009975
GO:0016829
GO:0016849
GO:0019934
GO:0020037
GO:0032991
GO:0035556
GO:0038023
GO:0038060
GO:0044877
GO:0046872
GO:0047805
GO:0051879
GO:0055086
GO:0060089
GO:0070026
GO:0070482
GO:0071732
GO:0098831
GO:0098978
GO:1901135
HMNXSV003032245
HMNXSV003052164
Hs.77890.0.S2_3p_at
ILMN_1782567
PH_hs_0004498
TC04000788.hg
X66533_at
g2746082_3p_a_at
Participates
as a member of
Guanylate cyclase soluble subunit beta [cytosol] (Homo sapiens)
Inferred To
Guanylate cyclase soluble subunit beta-1 [cytosol]
(Rattus norvegicus)
Gycbeta100B [cytosol]
(Drosophila melanogaster)
GUCY1B3 [cytosol]
(Bos taurus)
GUCY1B3 [cytosol]
(Canis familiaris)
GUCY1B3 [cytosol]
(Gallus gallus)
GUCY1B3 [cytosol]
(Mus musculus)
GUCY1B3 [cytosol]
(Sus scrofa)
gucy1b1 [cytosol]
(Danio rerio)
Cross References
Guide to Pharmacology - Targets
1290
ENSEMBL
ENST00000503520
,
ENSP00000426319
,
ENST00000264424
,
ENSP00000264424
,
ENST00000505764
,
ENSP00000420842
OpenTargets
ENSG00000061918
HPA
ENSG00000061918-GUCY1B1
PRO
Q02153
Pharos - Targets
Q02153
HMDB Protein
HMDBP01064
PDB
5MNW
,
4NI2
,
7D9S
,
6JT1
,
6JT0
,
8HBE
,
7D9T
,
6JT2
,
7D9U
,
7D9R
,
2WZ1
,
3UVJ
,
8HBH
,
8HBF
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