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OPN5 [photoreceptor disc membrane]
Stable Identifier
R-HSA-391831
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
photoreceptor disc membrane
Synonyms
Opsin-5, RecName: Full=Opsin-5; AltName: Full=Neuropsin; AltName: Full=G-protein coupled receptor 136; AltName: Full=G-protein coupled receptor PGR12; AltName: Full=Transmembrane protein 13;
GN Name=OPN5; Synonyms=GPR136, PGR12, TMEM13;
OS Homo sapiens, OPN5_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Homo sapiens)
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
Opsins act as GEFs for G alpha-t (Homo sapiens)
G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
Opsins binds G alpha-t (Homo sapiens)
G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Opsins (Homo sapiens)
Light stimulates opsin receptors (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
Opsins:photon [photoreceptor disc membrane] (Homo sapiens)
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
OPN5 [photoreceptor disc membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6U736 OPN5
Gene Names
OPN5, GPR136, PGR12, TMEM13
Chain
chain:1-354
Reference Genes
BioGPS Gene:221391 OPN5
COSMIC (genes):OPN5 OPN5
CTD Gene:221391 OPN5
dbSNP Gene:221391 OPN5
ENSEMBL:ENSG00000124818 OPN5
HGNC:19992 OPN5
KEGG:hsa:221391 OPN5
Monarch:221391 OPN5
NCBI Gene:221391 OPN5
OMIM:609042 OPN5
UCSC:Q6U736 OPN5
Reference Transcript
RefSeq:NM_181744.3 OPN5
Other Identifiers
11735809_a_at
11737516_a_at
1568914_PM_at
1568914_at
17009461
221391
233657_PM_at
233657_at
2909541
2909542
2909543
2909546
2909547
2909548
2909549
2909552
2909553
2909554
2909555
2909564
2909565
2909566
2909567
2909568
2909569
2909572
62448_at
8120151
A_23_P58934
A_33_P3404970
A_33_P3404974
GE492182
GE578108
GO:0004930
GO:0005502
GO:0005737
GO:0005886
GO:0007186
GO:0007601
GO:0007602
GO:0007604
GO:0008020
GO:0008289
GO:0009584
GO:0009881
GO:0016020
GO:0043153
GO:0050877
GO:0060089
GO:0071482
GO:0071492
GO:1990384
HMNXSV003033996
Hs.307115.0.S1_3p_at
Hs.307115.0.S1_3p_s_at
Hs2.213717.1.S1_3p_at
ILMN_1665180
ILMN_1784818
PH_hs_0035700
TC06000637.hg
TC06002818.hg
Participates
as a candidate of
Light-sensing opsins [photoreceptor disc membrane] (Homo sapiens)
Inferred To
opn5 [photoreceptor disc membrane]
(Danio rerio)
Opn5 [photoreceptor disc membrane]
(Mus musculus)
Opn5 [photoreceptor disc membrane]
(Rattus norvegicus)
OPN5 [photoreceptor disc membrane]
(Bos taurus)
OPN5 [photoreceptor disc membrane]
(Caenorhabditis elegans)
OPN5 [photoreceptor disc membrane]
(Canis familiaris)
OPN5 [photoreceptor disc membrane]
(Gallus gallus)
OPN5 [photoreceptor disc membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
161
ENSEMBL
ENSP00000360255
,
ENST00000371211
OpenTargets
ENSG00000124818
HPA
ENSG00000124818-OPN5
PRO
Q6U736
Pharos - Targets
Q6U736
GlyGen
Q6U736
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