Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
TAAR8 [plasma membrane]
Stable Identifier
R-HSA-391199
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
RecName: Full=Trace amine-associated receptor 8; AltName: Full=Trace amine receptor 5; Short=TaR-5; AltName: Full=G-protein coupled receptor 102; GN Name=TAAR8; Synonyms=GPR102, TA5, TAR5, TRAR5; OS Homo sapiens, TAAR8_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
Trace amine-associated receptors can bind trace amines (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR8 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q969N4 TAAR8
Gene Names
TAAR8, GPR102, TA5, TAR5, TRAR5
Chain
chain:1-342
Reference Genes
BioGPS Gene:83551 TAAR8
COSMIC (genes):TAAR8 TAAR8
CTD Gene:83551 TAAR8
dbSNP Gene:83551 TAAR8
ENSEMBL:ENSG00000146385 TAAR8
HGNC:14964 TAAR8
KEGG Gene (Homo sapiens):83551 TAAR8
Monarch:83551 TAAR8
NCBI Gene:83551 TAAR8
OMIM:606927 TAAR8
UCSC:Q969N4 TAAR8
Reference Transcript
RefSeq:NM_053278.2 TAAR8
Other Identifiers
0000610338
11743211_at
1553552_at
17012692
2926138
2926139
2926140
2926141
2926142
8122129
83551
A_14_P113930
A_23_P8269
GE473849
GO:0001594
GO:0003674
GO:0004930
GO:0005575
GO:0005886
GO:0007165
GO:0007186
GO:0008150
GO:0016020
GO:0016021
Hs2.350571.1.S1_3p_at
ILMN_1772523
PH_hs_0032780
TC06000993.hg
Participant Of
hasCandidate
Trace amine-associated receptor [plasma membrane]
Inferred To
taar13e [plasma membrane] (Danio rerio)
Homologues of TAAR8 [plasma membrane] (Danio rerio)
taar13c [plasma membrane] (Danio rerio)
taar13b [plasma membrane] (Danio rerio)
LOC516101 [plasma membrane] (Bos taurus)
Taar8b [plasma membrane] (Mus musculus)
mAChR-C [plasma membrane] (Drosophila melanogaster)
taar13a [plasma membrane] (Danio rerio)
TAAR8 [plasma membrane] (Sus scrofa)
taar13d [plasma membrane] (Danio rerio)
Cross References
RefSeq
NP_444508.1
OpenTargets
ENSG00000146385
HPA
ENSG00000146385-TAAR8
GeneCards
Q969N4
Ensembl
ENST00000275200
,
ENSG00000146385
,
ENSP00000275200
PRO
Q969N4
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text