Association of TriC/CCT with target proteins during biosynthesis

Stable Identifier
R-HSA-390471
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Association of TriC/CCT with target proteins during biosynthesis
Click the image above or here to open this pathway in the Pathway Browser
TRiC has broad recognition specificities, but in the cell it interacts with only a defined set of substrates (Yam et al. 2008). Many of its substrates that are targeted during biosynthesis are conserved between mammals and yeast (Yam et al. 2008).
Literature References
PubMed ID Title Journal Year
19011634 Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies

Lin, HT, Burlingame, A, Frydman, J, Xia, Y, Gerstein, M, Yam, AY

Nat Struct Mol Biol 2008
Participants
Events
Participates
as an event of
Orthologous Events
Association of TriC/CCT with target proteins during biosynthesis (Bos taurus)
Association of TriC/CCT with target proteins during biosynthesis (Caenorhabditis elegans)
Association of TriC/CCT with target proteins during biosynthesis (Canis familiaris)
Association of TriC/CCT with target proteins during biosynthesis (Dictyostelium discoideum)
Association of TriC/CCT with target proteins during biosynthesis (Drosophila melanogaster)
Association of TriC/CCT with target proteins during biosynthesis (Gallus gallus)
Association of TriC/CCT with target proteins during biosynthesis (Mus musculus)
Association of TriC/CCT with target proteins during biosynthesis (Rattus norvegicus)
Association of TriC/CCT with target proteins during biosynthesis (Saccharomyces cerevisiae)
Association of TriC/CCT with target proteins during biosynthesis (Schizosaccharomyces pombe)
Association of TriC/CCT with target proteins during biosynthesis (Sus scrofa)
Authored
Matthews, L  (2008-12-01)
Reviewed
Cowan, NJ  (2009-01-21)
Created
Matthews, L  (2009-02-09)
Cite Us!