Upon complex formation with STRAD and MO25, LKB1 (also known as serine/threonine kinase 11, STK11) is mostly cytosolic. LKB1 attains 20x activity towards the substrates belonging to the subfamily of AMPK-like kinases (5'AMP-activated protein kinases).
Clevers, HC, Medema, R, Smit, L, Alessi, DR, Baas, AF, Morrice, NA, Sapkota, GP, Boudeau, J
Prescott, AR, Clevers, HC, Schutkowski, M, Kieloch, A, Alessi, DR, Deak, M, Baas, AF, Morrice, NA, Boudeau, J
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