AP-1 transcription factor binds IGFBP7 promoter

Stable Identifier
R-HSA-3797196
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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AP-1 transcription factor binds IGFBP7 promoter
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FOS:JUN (AP-1) transcription factor, formed in response to oncogenic RAF-MAPK signaling which also triggers oxidative stress, binds the promoter of IGFBP7 gene (Wajapeyee et al. 2008).

Literature References
PubMed ID Title Journal Year
18267069 Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7

Wajapeyee, N, Serra, RW, Zhu, X, Mahalingam, M, Green, MR

Cell 2008
Participants
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Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2013-07-15)
Reviewed
Samarajiwa, S  (2013-09-03)
Created
Orlic-Milacic, M  (2013-07-05)