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TARS [cytosol]
Stable Identifier
R-HSA-379682
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Threonyl-tRNA synthetase
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
tRNA Aminoacylation (Homo sapiens)
Cytosolic tRNA aminoacylation (Homo sapiens)
threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate (Homo sapiens)
TARS dimer [cytosol] (Homo sapiens)
TARS [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P26639 TARS1
Gene Names
TARS1, TARS
Chain
chain:1-723
Reference Genes
BioGPS Gene:6897 TARS1
COSMIC (genes):TARS TARS1
CTD Gene:6897 TARS1
dbSNP Gene:6897 TARS1
ENSEMBL:ENSG00000113407 TARS
HGNC:11572 TARS1
Monarch:6897 TARS1
NCBI Gene:6897 TARS1
OMIM:187790 TARS1
UCSC:P26639 TARS1
Reference Transcript
RefSeq:NM_152295.4 TARS1
RefSeq:NM_001258438.1 TARS1
RefSeq:NM_001258437.1 TARS1
Other Identifiers
11716789_s_at
11716790_x_at
11744757_a_at
16983800
201263_PM_at
201263_at
240206_PM_at
240206_at
2805792
2805793
2805794
2805795
2805796
2805797
2805798
2805799
2805801
2805802
2805803
2805804
2805805
2805806
2805807
2805808
2805809
2805810
2805811
2805812
2805813
2805814
2805815
2805816
2805817
2805819
2805820
2805821
2805822
2805823
2805824
2805825
2805826
2805827
2805828
38473_at
58855_at
6897
8104760
A_14_P107412
A_23_P70168
GE58025
GE623291
GO:0000049
GO:0000166
GO:0003723
GO:0003824
GO:0004812
GO:0004829
GO:0005515
GO:0005524
GO:0005737
GO:0005829
GO:0006399
GO:0006412
GO:0006418
GO:0006435
GO:0006520
GO:0008270
GO:0016874
GO:0042802
GO:0043039
GO:0043226
GO:0070062
GO:0140098
HMNXSV003039310
Hs.118163.0.A1_3p_at
ILMN_1685480
M63180_at
PH_hs_0029021
TC05000148.hg
g4507366_3p_at
Participates
as a component of
TARS dimer [cytosol] (Homo sapiens)
Cross References
ENSEMBL
ENST00000455217
,
ENSP00000387710
,
ENST00000265112
,
ENSP00000424387
,
ENSP00000265112
,
ENST00000502553
OpenTargets
ENSG00000113407
HPA
ENSG00000113407-TARS1
ZINC - Substances
SYTC_HUMAN
ZINC target
P26639
PRO
P26639
Pharos - Targets
P26639
GlyGen
P26639
Orphanet
TARS1
ZINC - Predictions - Purchasable
SYTC_HUMAN
HMDB Protein
HMDBP00581
PDB
4P3N
,
1WWT
,
4HWT
,
4TTV
,
5XLN
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96CV9 OPTN
6
p-S177,S473,S513-OPTN [cytosol]
(R-HSA-9687840)
OPTN [cytosol]
(R-HSA-9687907)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [recycling endosome membrane]
(R-HSA-8854141)
0.556
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
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