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Laminin-332 binds collagen type VII
Stable Identifier
R-HSA-3787997
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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Extracellular matrix organization (Homo sapiens)
Laminin interactions (Homo sapiens)
Laminin-332 binds collagen type VII (Homo sapiens)
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Laminin-332 (laminin-5) consists of laminin alpha-3, beta-3 and gamma-2 chains. It is epithelial-basement membrane specific. It directly interacts with the NC1 domain of Collagen type VII through the N-terminus of the beta-3 laminin subunit and, to a lesser extent, the gamma-2 laminin subunit (Rousselle et al. 1997, Chen et al. 1999, Brittingham et al. 2006).
Literature References
PubMed ID
Title
Journal
Year
9245798
Laminin 5 binds the NC-1 domain of type VII collagen
Rest, M
,
Rousselle, P
,
Burgeson, RE
,
Champliaud, MF
,
Keene, DR
,
Ruggiero, F
J. Cell Biol.
1997
Participants
Input
Collagen type VII fibril [extracellular region]
(Homo sapiens)
Laminin-332 [extracellular region]
(Homo sapiens)
Output
Collagen type VII fibril:Laminin-332 [extracellular region]
(Homo sapiens)
Participates
as an event of
Laminin interactions (Homo sapiens)
Authored
Jupe, S (2012-08-08)
Reviewed
Ricard-Blum, S (2013-08-13)
Created
Jupe, S (2013-07-04)
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