Laminin-332 (laminin-5) consists of laminin alpha-3, beta-3 and gamma-2 chains. It is epithelial-basement membrane specific. It directly interacts with the NC1 domain of Collagen type VII through the N-terminus of the beta-3 laminin subunit and, to a lesser extent, the gamma-2 laminin subunit (Rousselle et al. 1997, Chen et al. 1999, Brittingham et al. 2006).