Laminin-332 binds collagen type VII

Stable Identifier
R-HSA-3787997
Type
Reaction
Species
Homo sapiens
Compartment
extracellular region
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Laminin-332 binds collagen type VII
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Laminin-332 (laminin-5) consists of laminin alpha-3, beta-3 and gamma-2 chains. It is epithelial-basement membrane specific. It directly interacts with the NC1 domain of Collagen type VII through the N-terminus of the beta-3 laminin subunit and, to a lesser extent, the gamma-2 laminin subunit (Rousselle et al. 1997, Chen et al. 1999, Brittingham et al. 2006).

Literature References
PubMed ID Title Journal Year
9245798 Laminin 5 binds the NC-1 domain of type VII collagen

Rest, M, Rousselle, P, Burgeson, RE, Champliaud, MF, Keene, DR, Ruggiero, F

J. Cell Biol. 1997
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Orthologous Events
Laminin-332 binds collagen type VII (Canis familiaris)
Laminin-332 binds collagen type VII (Mus musculus)
Authored
Jupe, S  (2012-08-08)
Reviewed
Ricard-Blum, S  (2013-08-13)
Created
Jupe, S  (2013-07-04)
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