Laminin-332 binds collagen type VII

Stable Identifier
R-HSA-3787997
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Laminin-332 (laminin-5) consists of laminin alpha-3, beta-3 and gamma-2 chains. It is epithelial-basement membrane specific. It directly interacts with the NC1 domain of Collagen type VII through the N-terminus of the beta-3 laminin subunit and, to a lesser extent, the gamma-2 laminin subunit (Rousselle et al. 1997, Chen et al. 1999, Brittingham et al. 2006).

Literature References
PubMed ID Title Journal Year
9245798 Laminin 5 binds the NC-1 domain of type VII collagen

Rousselle, P, Keene, DR, Ruggiero, F, Champliaud, MF, Rest, M, Burgeson, RE

J. Cell Biol. 1997
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created