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PPP1R3C binds to glycogen:GYG1:GYS1
Stable Identifier
R-HSA-3781023
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycogen metabolism (Homo sapiens)
Glycogen synthesis (Homo sapiens)
PPP1R3C binds to glycogen:GYG1:GYS1 (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C, PTG) binds to glycogen particles containing GYG1 (glycogenin 1) and GYS1 (glycogen synthase 1). PPP1R3C appears to function as a scaffolding protein to mediate association of other proteins with glycogen granules and to promote the synthesis of glycogen (Worby et al. 2008).
Literature References
PubMed ID
Title
Journal
Year
18070875
Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
Gentry, MS
,
Worby, CA
,
Dixon, JE
J. Biol. Chem.
2008
Participants
Input
glycogen-GYG1:GYS1-a tetramer [cytosol]
(Homo sapiens)
PPP1R3C [cytosol]
(Homo sapiens)
Output
PPP1R3C:glycogen-GYG1:GYS1-a tetramer [cytosol]
(Homo sapiens)
Participates
as an event of
Glycogen synthesis (Homo sapiens)
Orthologous Events
PPP1R3C binds to glycogen:GYG1:GYS1 (Bos taurus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Caenorhabditis elegans)
PPP1R3C binds to glycogen:GYG1:GYS1 (Canis familiaris)
PPP1R3C binds to glycogen:GYG1:GYS1 (Danio rerio)
PPP1R3C binds to glycogen:GYG1:GYS1 (Drosophila melanogaster)
PPP1R3C binds to glycogen:GYG1:GYS1 (Gallus gallus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Mus musculus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Rattus norvegicus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Saccharomyces cerevisiae)
PPP1R3C binds to glycogen:GYG1:GYS1 (Sus scrofa)
Authored
D'Eustachio, P (2013-07-19)
Reviewed
Jassal, B (2013-07-26)
Pederson, B (2014-02-19)
Created
D'Eustachio, P (2013-06-28)
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