PPP1R3C binds to glycogen:GYG1:GYS1

Stable Identifier
R-HSA-3781023
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
4/5
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PPP1R3C binds to glycogen:GYG1:GYS1
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Protein phosphatase 1 regulatory subunit 3C (PPP1R3C, PTG) binds to glycogen particles containing GYG1 (glycogenin 1) and GYS1 (glycogen synthase 1). PPP1R3C appears to function as a scaffolding protein to mediate association of other proteins with glycogen granules and to promote the synthesis of glycogen (Worby et al. 2008).
Literature References
PubMed ID Title Journal Year
18070875 Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)

Worby, CA, Gentry, MS, Dixon, JE

J. Biol. Chem. 2008
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Catalyst Activity

protein-macromolecule adaptor activity of PPP1R3C [cytosol]

Physical Entity
PPP1R3C [cytosol] (Homo sapiens)
Activity
protein-macromolecule adaptor activity (GO:0030674)
Orthologous Events
PPP1R3C binds to glycogen:GYG1:GYS1 (Bos taurus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Caenorhabditis elegans)
PPP1R3C binds to glycogen:GYG1:GYS1 (Canis familiaris)
PPP1R3C binds to glycogen:GYG1:GYS1 (Danio rerio)
PPP1R3C binds to glycogen:GYG1:GYS1 (Drosophila melanogaster)
PPP1R3C binds to glycogen:GYG1:GYS1 (Gallus gallus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Mus musculus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Rattus norvegicus)
PPP1R3C binds to glycogen:GYG1:GYS1 (Saccharomyces cerevisiae)
PPP1R3C binds to glycogen:GYG1:GYS1 (Sus scrofa)
Authored
D'Eustachio, P  (2013-07-19)
Reviewed
Pederson, B  (2014-02-19)
Jassal, B  (2013-07-26)
Created
D'Eustachio, P  (2013-06-28)
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