PPP1R3C binds to glycogen:GYG2:GYS2

Stable Identifier
R-HSA-3780997
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Protein phosphatase 1 regulatory subunit 3C (PPP1R3C, PTG) binds to glycogen particles containing GYG2 (glycogenin 2) and GYS2 (glycogen synthase 2). PPP1R3C appears to function as a scaffolding protein to mediate association of other proteins with glycogen granules and to promote the synthesis of glycogen (Worby et al. 2008). This reaction, involving GYG and GYS isoforms largely expressed in the liver has not been studied in detail but is inferred from the better-characterized one involving GYG1- and GYS1-containing glycogen particles ("muscle" isoforms, widely expressed in the body outside the liver).

Literature References
PubMed ID Title Journal Year
18070875 Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)

Worby, CA, Gentry, MS, Dixon, JE

J. Biol. Chem. 2008
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