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NMBR [plasma membrane]
Stable Identifier
R-HSA-375357
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Neuromedin-B receptor, NMBR_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Bombesin-like receptors bind bombesin homologues (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
NMBR [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P28336 NMBR
Gene Names
NMBR
Chain
chain:1-390
Reference Genes
BioGPS Gene:4829 NMBR
COSMIC (genes):NMBR NMBR
CTD Gene:4829 NMBR
dbSNP Gene:4829 NMBR
ENSEMBL:ENSG00000135577 NMBR
HGNC:7843 NMBR
KEGG Gene (Homo sapiens):4829 NMBR
Monarch:4829 NMBR
NCBI Gene:4829 NMBR
OMIM:162341 NMBR
UCSC:P28336 NMBR
Reference Transcript
RefSeq:NM_001324308.1 NMBR
RefSeq:NM_002511.3 NMBR
RefSeq:NM_001324307.1 NMBR
Other Identifiers
0006020152
11736983_at
17024317
207333_PM_at
207333_at
2977125
2977126
2977127
2977128
2977129
2977130
2977131
2977132
2977133
2977134
2977140
33996_at
4829
80477_at
8129947
A_23_P70634
GO:0003674
GO:0004930
GO:0004946
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0005887
GO:0007165
GO:0007186
GO:0007200
GO:0007218
GO:0008150
GO:0008188
GO:0008528
GO:0016020
GO:0016021
GO:0031989
HMNXSV003033744
ILMN_1735704
M73482_at
PH_hs_0025990
TC06002177.hg
TC06002178.hg
g4505406_3p_at
Participates
as a member of
Bombesin-like receptor [plasma membrane] (Homo sapiens)
Inferred To
Nmbr [plasma membrane]
(Mus musculus)
Nmbr [plasma membrane]
(Rattus norvegicus)
NMBR [plasma membrane]
(Bos taurus)
NMBR [plasma membrane]
(Canis familiaris)
NMBR [plasma membrane]
(Gallus gallus)
NMBR [plasma membrane]
(Sus scrofa)
nmbr [plasma membrane]
(Danio rerio)
nmbr [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001311236.1
,
NP_001311237.1
,
NP_002502.2
Guide to Pharmacology - Targets
38
OpenTargets
ENSG00000135577
GeneCards
P28336
ZINC - Substances
NMBR_HUMAN
HPA
ENSG00000135577-NMBR
Ensembl
ENST00000258042
,
ENSP00000258042
,
ENSG00000135577
ZINC - Biogenic
NMBR_HUMAN
ZINC target
P28336
PRO
P28336
Pharos - Targets
P28336
ZINC - Predictions - Purchasable
NMBR_HUMAN
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