Phosphorylation and activation of Ezrin

Stable Identifier
R-HSA-374664
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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PIP2 places Ezrin at the membrane in a location to be phosphorylated, and thereby activated, by protein kinase-C theta.

Literature References
PubMed ID Title Journal Year
12154370 ERM proteins and merlin: integrators at the cell cortex

Bretscher, A, Edwards, K, Fehon, RG

Nat Rev Mol Cell Biol 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein kinase C activity of p-Y90,T538,S676,S695-PRKCQ [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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