Copper chaperone of superoxide dismutase (CCS) transfers a copper(I) atom to a SOD1 monomer that already contains a Zn atom (Culotta et al. 1997, Casareno et al. 1998, Rae et al. 2001, Brown et al. 2004, Banci et al. 2012). The reaction proceeds by a two step mechanism in which SOD1 first forms heterodimers with CCS (Rae et al. 2001, Banci et al. 2012).
Gitlin, JD, Casareno, RL, Culotta, VC, Krems, B, Strain, J, Klomp, LW
Gitlin, JD, Casareno, RL, Waggoner, D
Doan, PE, Brown, NM, O'Halloran, TV, Torres, AS
Banci, L, Kozyreva, T, Massagni, C, Zovo, K, Cantini, F, Palumaa, P, Rubino, JT, Bertini, I
Cizewski Culotta, V, Watson, WH, Whitson, LJ, Outten, CE, Carroll, MC, Jensen, LT, Hart, PJ, Rosenfeld, L, Proescher, JB
Kawamata, H, Manfredi, G
O'Halloran, TV, Torres, AS, Rae, TD, Pufahl, RA
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