The first step in the biogenesis of thyroid hormones is the oxidation of iodide (I-) by H2O2/peroxidase after being taken up by the thyroid gland. This event is known as organification.
Buxeraud, J, Raby, M, Thomes, JC, Raby, C, Lagorce, JF, Catanzano, G
peroxidase activity of TPO [plasma membrane]
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