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TAS2Rs:Bitter-tasting compounds
Stable Identifier
R-HSA-3299631
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)
T2Rs bind bitter-tasting compounds (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
Participants
components
Bitter-tasting compounds [extracellular region]
TAS2Rs [plasma membrane] (Homo sapiens)
Participant Of
hasMember
Ligand:GPCR complexes that activate Gi [plasma membrane]
output
T2Rs bind bitter-tasting compounds
Inferred To
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Bos taurus)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Canis familiaris)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Rattus norvegicus)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Taeniopygia guttata)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Xenopus tropicalis)
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