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E2F1/2/3:DP1/2 binds SUZ12 gene promoter
Stable Identifier
R-HSA-3240766
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cellular responses to stimuli (Homo sapiens)
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Cellular Senescence (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
E2F1/2/3:DP1/2 binds SUZ12 gene promoter (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
E2F1, E2F2, E2F3 and E2F4 are all able to bind the promoter of SUZ12 (ChET 9) (Weinmann et al 2001), a subunit of the Polycomb repressor complex 2 (PRC2).
Literature References
PubMed ID
Title
Journal
Year
11564866
Use of chromatin immunoprecipitation to clone novel E2F target promoters
Bartley, SM
,
Weinmann, AS
,
Farnham, PJ
,
Zhang, T
,
Zhang, MQ
Mol. Cell. Biol.
2001
Participants
Input
E2F1,E2F2,E2F3:TFDP1,TFDP2 [nucleoplasm]
(Homo sapiens)
SUZ12 Gene [nucleoplasm]
(Homo sapiens)
Output
SUZ12 Gene:E2F1/2/3:DP1/2 [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Oxidative Stress Induced Senescence (Homo sapiens)
Authored
Orlic-Milacic, M (2013-07-15)
Reviewed
Samarajiwa, S (2013-09-03)
Created
Orlic-Milacic, M (2013-03-28)
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