DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm]

Stable Identifier
R-HSA-3211699
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
The Polycomb Repressor Complex 2 (PRC2) is able to interact with and recruit DNMT1, DNMT3a, and DNMT3b, all of which transfer a methyl group from S-adenosylmethionine to the 5 position of the cytosine ring.EZH2 is required for DNA methylation at PRC2 targets.
Participants
components
Participates
as an output of
Inferred To
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Bos taurus)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Danio rerio)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Drosophila melanogaster)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Gallus gallus)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Rattus norvegicus)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Sus scrofa)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Xenopus tropicalis)
Cite Us!