Reactome | AOX1 [cytosol]

AOX1 [cytosol]

Stable Identifier

R-HSA-3204326

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Aldehyde oxidase ecNumber1.2.3.1/ecNumber, ADO_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism (Homo sapiens)

- Metabolism of vitamins and cofactors (Homo sapiens)
  - Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
    - Vitamin B6 activation to pyridoxal phosphate (Homo sapiens)
      - AOX1 oxidises PXL to PDXate (Homo sapiens)
        
        2xAOX1:cofactors [cytosol] (Homo sapiens)
        
        AOX1:cofactors [cytosol] (Homo sapiens)
        
        AOX1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q06278 AOX1

Gene Names

AOX1, AO

Chain

chain:1-1338

Reference Genes

BioGPS Gene:316 AOX1

COSMIC (genes):AOX1 AOX1

CTD Gene:316 AOX1

dbSNP Gene:316 AOX1

ENSEMBL:ENSG00000138356 AOX1

ENSEMBL_homo_sapiens_GENE:ENSG00000138356.14 AOX1

HGNC:553 AOX1

KEGG Gene (Homo sapiens):316 AOX1

Monarch:316 AOX1

NCBI Gene:316 AOX1

OMIM:602841 AOX1

UCSC:Q06278 AOX1

Reference Transcript

RefSeq:NM_001159.3 AOX1

Other Identifiers

11756912_a_at

16889268

205082_PM_s_at

205082_s_at

205083_PM_at

205083_at

2522250

2522251

2522252

2522254

2522257

2522258

2522259

2522261

2522262

2522264

2522265

2522266

2522267

2522268

2522269

2522271

2522274

2522276

2522280

2522282

2522283

2522284

2522285

2522286

2522290

2522292

2522294

2522295

2522296

2522298

2522302

2522304

2522306

2522307

2522309

2522310

2522312

2522313

2522314

2522315

316

37599_at

8047300

A_14_P103343

A_14_P121068

A_14_P130789

A_33_P3354414

GE60468

GO:0003824

GO:0004031

GO:0005506

GO:0005576

GO:0005615

GO:0005737

GO:0005829

GO:0006629

GO:0006805

GO:0016491

GO:0042802

GO:0042803

GO:0043226

GO:0043546

GO:0046872

GO:0050660

GO:0051287

GO:0051536

GO:0051537

GO:0070062

GO:0071949

ILMN_1767113

L11005_at

PH_hs_0019257

TC02001162.hg

g13516378_3p_a_at

g6598319_3p_at

Participates

as a component of

AOX1:cofactors [cytosol] (Homo sapiens)

Inferred To

AOX1 [cytosol] (Bos taurus)

AOX1 [cytosol] (Caenorhabditis elegans)

AOX1 [cytosol] (Danio rerio)

AOX1 [cytosol] (Dictyostelium discoideum)

AOX1 [cytosol] (Drosophila melanogaster)

AOX1 [cytosol] (Gallus gallus)

AOX1 [cytosol] (Mus musculus)

AOX1 [cytosol] (Rattus norvegicus)

AOX1 [cytosol] (Sus scrofa)

AOX1 [cytosol] (Xenopus tropicalis)

Homologues of AOX1 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001150.3

ZINC - World Drugs

AOXA_HUMAN

Guide to Pharmacology - Targets

3186

OpenTargets

ENSG00000138356

ZINC - FDA approved

AOXA_HUMAN

ZINC - Substances

AOXA_HUMAN

ZINC target

Q06278

ZINC - Biogenic

AOXA_HUMAN

PRO

Q06278

PDB

4UHX, 6Q6Q, 7OPN, 4UHW, 8EMT, 7ORC, 5EPG

ZINC - Investigational

AOXA_HUMAN

ZINC - Metabolites

AOXA_HUMAN

GeneCards

Q06278

HPA

ENSG00000138356-AOX1

Ensembl

ENSG00000138356, ENSP00000363832, ENST00000374700

Pharos - Targets

Q06278

ZINC - Predictions - Purchasable

AOXA_HUMAN

Orphanet

24345

HMDB Protein

HMDBP00126

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